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Buchwald Hartwig diversification of unprotected halotryptophans, halotryptophan containing tripeptides and the natural product barettin in aqueous conditions

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dc.contributor.authorRenault, Yohann J. G.
dc.contributor.authorLynch, Rosemary
dc.contributor.authorMarelli, Enrico
dc.contributor.authorSharma, Sunil V.
dc.contributor.authorPubill Ulldemolins, Cristina
dc.contributor.authorSharp, Joshua
dc.contributor.authorCartmell, Christopher
dc.contributor.authorCárdenas, Paco
dc.contributor.authorGoss, Rebecca J. M.
dc.date.accessioned2019-10-14T15:30:01Z
dc.date.available2019-10-14T15:30:01Z
dc.date.issued2019-10-08
dc.identifier259327007
dc.identifierf9e8cb82-6a7b-4253-9f1b-337ee6a66c59
dc.identifier85074873934
dc.identifier000496533500033
dc.identifier.citationRenault , Y J G , Lynch , R , Marelli , E , Sharma , S V , Pubill Ulldemolins , C , Sharp , J , Cartmell , C , Cárdenas , P & Goss , R J M 2019 , ' Buchwald Hartwig diversification of unprotected halotryptophans, halotryptophan containing tripeptides and the natural product barettin in aqueous conditions ' , Chemical Communications , vol. Advance Article . https://doi.org/10.1039/C9CC02554Een
dc.identifier.issn1359-7345
dc.identifier.urihttps://hdl.handle.net/10023/18661
dc.descriptionThe research leading to these results has received funding from the European Research Council under the European Union’s Seventh Framework Programme (FP7/2007-2013/ERC grant agreement no 614779 GenoChemetics (to R.J.M.G) P. Cárdenas received support from the European Union's Horizon 2020 research and innovation program through the SponGES project (grant agreement No. 679849).en
dc.description.abstractBlending synthetic chemistry and biology is synthetically powerful. To further enable this, compatible synthetic tools are needed. We report the first Buchwald Hartwig amination reactions with unprotected halotryptophans in aqueous systems and demonstrate this methodology applicable to the modification of unprotected halotryptophans, simple tripeptides and the natural product barettin.
dc.format.extent4
dc.format.extent1901566
dc.language.isoeng
dc.relation.ispartofChemical Communicationsen
dc.subjectQD Chemistryen
dc.subject.lccQDen
dc.titleBuchwald Hartwig diversification of unprotected halotryptophans, halotryptophan containing tripeptides and the natural product barettin in aqueous conditionsen
dc.typeJournal itemen
dc.contributor.sponsorEuropean Research Councilen
dc.contributor.institutionUniversity of St Andrews. School of Chemistryen
dc.contributor.institutionUniversity of St Andrews. Biomedical Sciences Research Complexen
dc.contributor.institutionUniversity of St Andrews. EaSTCHEMen
dc.identifier.doi10.1039/C9CC02554E
dc.description.statusPeer revieweden
dc.date.embargoedUntil2019-10-08
dc.identifier.grantnumberGCGXCen


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