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Formal synthesis of (+)-lactacystin from L-serine

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dc.contributor.authorPage, Philip C. Bulman
dc.contributor.authorGoodyear, Ross L.
dc.contributor.authorChan, Yohan
dc.contributor.authorSlawin, Alexandra M. Z.
dc.contributor.authorAllin, Steven M.
dc.date.accessioned2019-10-09T14:30:07Z
dc.date.available2019-10-09T14:30:07Z
dc.date.issued2019-09-24
dc.identifier261680995
dc.identifier91f2b422-66fe-4840-97a1-94511e5464a9
dc.identifier000487364400065
dc.identifier85072662372
dc.identifier.citationPage , P C B , Goodyear , R L , Chan , Y , Slawin , A M Z & Allin , S M 2019 , ' Formal synthesis of (+)-lactacystin from L-serine ' , RSC Advances , vol. 9 , no. 51 , pp. 30019-30032 . https://doi.org/10.1039/c9ra07244fen
dc.identifier.issn2046-2069
dc.identifier.otherORCID: /0000-0002-9527-6418/work/63045016
dc.identifier.urihttps://hdl.handle.net/10023/18631
dc.descriptionThis investigation has enjoyed the support of Charnwood Molecular Ltd and the University of East Anglia.en
dc.description.abstractA formal, stereocontrolled synthesis of lactacystin has been completed from t-Bu-O-L-serine, providing the key intermediate 13 , also useful for the generation of a range of C-9 analogues.
dc.format.extent14
dc.format.extent1197450
dc.language.isoeng
dc.relation.ispartofRSC Advancesen
dc.subjectQD Chemistryen
dc.subjectDASen
dc.subject.lccQDen
dc.titleFormal synthesis of (+)-lactacystin from L-serineen
dc.typeJournal articleen
dc.contributor.institutionUniversity of St Andrews. School of Chemistryen
dc.contributor.institutionUniversity of St Andrews. EaSTCHEMen
dc.identifier.doi10.1039/c9ra07244f
dc.description.statusPeer revieweden


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