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dc.contributor.authorTauber, Nina M.
dc.contributor.authorO'Toole, Mia S.
dc.contributor.authorDinkel, Andreas
dc.contributor.authorGalica, Jacqueline
dc.contributor.authorHumphris, Gerry
dc.contributor.authorLebel, Sophie
dc.contributor.authorMaheu, Christine
dc.contributor.authorOzakinci, Gozde
dc.contributor.authorPrins, Judith
dc.contributor.authorSharpe, Louise
dc.contributor.authorSmith, Allan 'Ben'
dc.contributor.authorThewes, Belinda
dc.contributor.authorSimard, Sébastien
dc.contributor.authorZachariae, Robert
dc.identifier.citationTauber , N M , O'Toole , M S , Dinkel , A , Galica , J , Humphris , G , Lebel , S , Maheu , C , Ozakinci , G , Prins , J , Sharpe , L , Smith , A B , Thewes , B , Simard , S & Zachariae , R 2019 , ' Effect of psychological intervention on fear of cancer recurrence : a systematic review and meta-analysis ' , Journal of Clinical Oncology , vol. 37 .
dc.identifier.otherPURE: 259451940
dc.identifier.otherPURE UUID: 0d6e1271-505d-4c85-bc06-0801be9fd4aa
dc.identifier.otherScopus: 85074304461
dc.identifier.otherWOS: 000501780200011
dc.descriptionThe study was supported in part by the Danish Cancer Society, Grant# R150-A10080en
dc.description.abstractPurpose Fear of cancer recurrence (FCR) is a significantly distressing problem that affects a substantial number of patients with and survivors of cancer; however, the overall efficacy of available psychological interventions on FCR remains unknown. We therefore evaluated this in the present systematic review and meta-analysis. Methods We searched key electronic databases to identify trials that evaluated the effect of psychological interventions on FCR among patients with and survivors of cancer. Controlled trials were subjected to meta-analysis, and the moderating influence of study characteristics on the effect were examined. Overall quality of evidence was evaluated using the GRADE system. Open trials were narratively reviewed to explore ongoing developments in the field (PROSPERO registration no.: CRD42017076514). Results A total of 23 controlled trials (21 randomized controlled trials) and nine open trials were included. Small effects (Hedges’s g) were found both at postintervention (g = 0.33; 95% CI, 0.20 to 0.46; P < .001) and at follow-up (g = 0.28; 95% CI, 0.17 to 0.40; P < .001). Effects at postintervention of contemporary cognitive behavioral therapies (CBTs; g = 0.42) were larger than those of traditional CBTs (g = 0.24; β = .22; 95% CI, .04 to .41; P = .018). At follow-up, larger effects were associated with shorter time to follow-up (β = −.01; 95% CI, −.01 to −.00; P = .027) and group-based formats (β = .18; 95% CI, .01 to .36; P = .041). A GRADE evaluation indicated evidence of moderate strength for effects of psychological intervention for FCR. Conclusion Psychological interventions for FCR revealed a small but robust effect at postintervention, which was largely maintained at follow-up. Larger postintervention effects were found for contemporary CBTs that were focused on processes of cognition—for example, worry, rumination, and attentional bias—rather than the content, and aimed to change the way in which the individual relates to his or her inner experiences. Future trials could investigate how to further optimize and tailor interventions to individual patients’ FCR presentation.
dc.relation.ispartofJournal of Clinical Oncologyen
dc.rightsCopyright © 2019 by American Society of Clinical Oncology. Licensed under the Creative Commons Attribution 4.0 license.en
dc.subjectBF Psychologyen
dc.subjectRC0254 Neoplasms. Tumors. Oncology (including Cancer)en
dc.subjectSDG 3 - Good Health and Well-beingen
dc.titleEffect of psychological intervention on fear of cancer recurrence : a systematic review and meta-analysisen
dc.typeJournal itemen
dc.description.versionPublisher PDFen
dc.contributor.institutionUniversity of St Andrews. Sir James Mackenzie Institute for Early Diagnosisen
dc.contributor.institutionUniversity of St Andrews. Population and Behavioural Science Divisionen
dc.contributor.institutionUniversity of St Andrews. WHO Collaborating Centre for International Child & Adolescent Health Policyen
dc.contributor.institutionUniversity of St Andrews. Health Psychologyen
dc.contributor.institutionUniversity of St Andrews. St Andrews Sustainability Instituteen
dc.contributor.institutionUniversity of St Andrews. School of Medicineen
dc.description.statusPeer revieweden

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