Multi-part balanced incomplete-block designs

Bailey, R. A.; Cameron, Peter J.

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Date

18/04/2019

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Abstract

We consider designs for cancer trials which allow each medical centre to treat only a limited number of cancer types with only a limited number of drugs. We specify desirable properties of these designs, and prove some consequences. Then we give several different constructions. Finally we generalize this to three or more factors, such as biomarkers.

Citation

Bailey , R A & Cameron , P J 2019 , ' Multi-part balanced incomplete-block designs ' , Statistical Papers , vol. 60 , no. 2 , pp. 405-426 . https://doi.org/10.1007/s00362-018-01071-x

Publication

Statistical Papers

Status

Peer reviewed

DOI

https://doi.org/10.1007/s00362-018-01071-x

ISSN

0932-5026

Type

Journal article

Rights

© The Author(s) 2019. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

Collections

University of St Andrews Research

URI

http://hdl.handle.net/10023/16933