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Sharpening emitter localization in front of a tuned mirror

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dc.contributor.authorHeil, Hannah S.
dc.contributor.authorSchreiber, Benjamin
dc.contributor.authorGötz, Ralph
dc.contributor.authorEmmerling, Monika
dc.contributor.authorDabauvalle, Marie-Christine
dc.contributor.authorKrohne, Georg
dc.contributor.authorHöfling, Sven
dc.contributor.authorKamp, Martin
dc.contributor.authorSauer, Markus
dc.contributor.authorHeinze, Katrin G.
dc.date.accessioned2018-12-10T13:30:06Z
dc.date.available2018-12-10T13:30:06Z
dc.date.issued2018-12-05
dc.identifier.citationHeil , H S , Schreiber , B , Götz , R , Emmerling , M , Dabauvalle , M-C , Krohne , G , Höfling , S , Kamp , M , Sauer , M & Heinze , K G 2018 , ' Sharpening emitter localization in front of a tuned mirror ' , Light: Science & Applications , vol. 7 , 99 . https://doi.org/10.1038/s41377-018-0104-zen
dc.identifier.issn2047-7538
dc.identifier.otherPURE: 256639986
dc.identifier.otherPURE UUID: bfc8607e-86c0-4c30-9d70-0f6301e97d9a
dc.identifier.otherScopus: 85057608807
dc.identifier.otherWOS: 000452471700001
dc.identifier.urihttps://hdl.handle.net/10023/16659
dc.description.abstractSingle-molecule localization microscopy (SMLM) aims for maximized precision and a high signal-to-noise ratio1. Both features can be provided by placing the emitter in front of a metal-dielectric nanocoating that acts as a tunedmirror2–4. Here, we demonstrate that a higher photon yield at a lower background on biocompatible metal-dielectric nanocoatings substantially improves SMLM performance and increases the localization precision by up to a factor oftwo. The resolution improvement relies solely on easy-to-fabricate nanocoatings on standard glass coverslips and is spectrally and spatially tunable by the layer design and wavelength, as experimentally demonstrated for dual-color SMLM in cells.
dc.format.extent8
dc.language.isoeng
dc.relation.ispartofLight: Science & Applicationsen
dc.rights© The Author(s) 2018. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/en
dc.subjectQC Physicsen
dc.subjectTK Electrical engineering. Electronics Nuclear engineeringen
dc.subjectNDASen
dc.subject.lccQCen
dc.subject.lccTKen
dc.titleSharpening emitter localization in front of a tuned mirroren
dc.typeJournal articleen
dc.description.versionPublisher PDFen
dc.contributor.institutionUniversity of St Andrews. Condensed Matter Physicsen
dc.contributor.institutionUniversity of St Andrews. School of Physics and Astronomyen
dc.identifier.doihttps://doi.org/10.1038/s41377-018-0104-z
dc.description.statusPeer revieweden


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