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Sharpening emitter localization in front of a tuned mirror
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dc.contributor.author | Heil, Hannah S. | |
dc.contributor.author | Schreiber, Benjamin | |
dc.contributor.author | Götz, Ralph | |
dc.contributor.author | Emmerling, Monika | |
dc.contributor.author | Dabauvalle, Marie-Christine | |
dc.contributor.author | Krohne, Georg | |
dc.contributor.author | Höfling, Sven | |
dc.contributor.author | Kamp, Martin | |
dc.contributor.author | Sauer, Markus | |
dc.contributor.author | Heinze, Katrin G. | |
dc.date.accessioned | 2018-12-10T13:30:06Z | |
dc.date.available | 2018-12-10T13:30:06Z | |
dc.date.issued | 2018-12-05 | |
dc.identifier | 256639986 | |
dc.identifier | bfc8607e-86c0-4c30-9d70-0f6301e97d9a | |
dc.identifier | 85057608807 | |
dc.identifier | 000452471700001 | |
dc.identifier.citation | Heil , H S , Schreiber , B , Götz , R , Emmerling , M , Dabauvalle , M-C , Krohne , G , Höfling , S , Kamp , M , Sauer , M & Heinze , K G 2018 , ' Sharpening emitter localization in front of a tuned mirror ' , Light: Science & Applications , vol. 7 , 99 . https://doi.org/10.1038/s41377-018-0104-z | en |
dc.identifier.issn | 2047-7538 | |
dc.identifier.uri | https://hdl.handle.net/10023/16659 | |
dc.description.abstract | Single-molecule localization microscopy (SMLM) aims for maximized precision and a high signal-to-noise ratio1. Both features can be provided by placing the emitter in front of a metal-dielectric nanocoating that acts as a tunedmirror2–4. Here, we demonstrate that a higher photon yield at a lower background on biocompatible metal-dielectric nanocoatings substantially improves SMLM performance and increases the localization precision by up to a factor oftwo. The resolution improvement relies solely on easy-to-fabricate nanocoatings on standard glass coverslips and is spectrally and spatially tunable by the layer design and wavelength, as experimentally demonstrated for dual-color SMLM in cells. | |
dc.format.extent | 8 | |
dc.format.extent | 3446992 | |
dc.language.iso | eng | |
dc.relation.ispartof | Light: Science & Applications | en |
dc.subject | QC Physics | en |
dc.subject | TK Electrical engineering. Electronics Nuclear engineering | en |
dc.subject | NDAS | en |
dc.subject.lcc | QC | en |
dc.subject.lcc | TK | en |
dc.title | Sharpening emitter localization in front of a tuned mirror | en |
dc.type | Journal article | en |
dc.contributor.institution | University of St Andrews. Condensed Matter Physics | en |
dc.contributor.institution | University of St Andrews. School of Physics and Astronomy | en |
dc.identifier.doi | 10.1038/s41377-018-0104-z | |
dc.description.status | Peer reviewed | en |
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