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dc.contributor.authorHaugland, Marius
dc.contributor.authorLovett, Janet Eleanor
dc.contributor.authorAnderson, Edward
dc.date.accessioned2018-12-01T00:50:35Z
dc.date.available2018-12-01T00:50:35Z
dc.date.issued2018-02-07
dc.identifier.citationHaugland , M , Lovett , J E & Anderson , E 2018 , ' Advances in the synthesis of nitroxide radicals for use in biomolecule spin labelling ' , Chemical Society Reviews , vol. 47 , no. 3 , pp. 668-680 . https://doi.org/10.1039/C6CS00550Ken
dc.identifier.issn0306-0012
dc.identifier.otherPURE: 251734603
dc.identifier.otherPURE UUID: aa80cea5-291e-44d2-890f-dc2d9d246578
dc.identifier.otherScopus: 85041406434
dc.identifier.otherWOS: 000424136900002
dc.identifier.urihttp://hdl.handle.net/10023/16602
dc.descriptionFunding: UK EPSRC (EP/L022044/1), and the Royal Society for a University Research Fellowship (JEL).en
dc.description.abstractEPR spectroscopy is an increasingly useful analytical tool to probe biomolecule structure, dynamic behaviour, and interactions. Nitroxide radicals are the most commonly used radical probe in EPR experiments, and many methods have been developed for their synthesis, as well as incorporation into biomolecules using site-directed spin labelling. In this Tutorial Review, we discuss the most practical methods for the synthesis of nitroxides, focusing on the tunability of their structures, the manipulation of their sidechains into spin labelling handles, and their installation into biomolecules.
dc.language.isoeng
dc.relation.ispartofChemical Society Reviewsen
dc.rights© 2017, the Author(s). This work has been made available online in accordance with the publisher’s policies. This is the author created, accepted version manuscript following peer review and may differ slightly from the final published version. The final published version of this work is available at https://doi.org/10.1039/C6CS00550Ken
dc.subjectNitroxide spin labelsen
dc.subjectEPR spectroscopyen
dc.subjectChemical synthesisen
dc.subjectQC Physicsen
dc.subjectQD Chemistryen
dc.subjectQH301 Biologyen
dc.subject.lccQCen
dc.subject.lccQDen
dc.subject.lccQH301en
dc.titleAdvances in the synthesis of nitroxide radicals for use in biomolecule spin labellingen
dc.typeJournal itemen
dc.description.versionPostprinten
dc.contributor.institutionUniversity of St Andrews.School of Physics and Astronomyen
dc.contributor.institutionUniversity of St Andrews.Biomedical Sciences Research Complexen
dc.identifier.doihttps://doi.org/10.1039/C6CS00550K
dc.description.statusPeer revieweden
dc.date.embargoedUntil2018-12-01


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