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dc.contributor.authorSivakumaran, Magali H.
dc.contributor.authorMacKenzie, Andrew K.
dc.contributor.authorCallan, Imogen R.
dc.contributor.authorAinge, James A.
dc.contributor.authorO'Connor, Akira R.
dc.date.accessioned2018-08-02T08:30:08Z
dc.date.available2018-08-02T08:30:08Z
dc.date.issued2018-08-01
dc.identifier255031176
dc.identifier5b629e09-980b-4899-a5d3-552bea4041c0
dc.identifier85050994577
dc.identifier000440412400001
dc.identifier.citationSivakumaran , M H , MacKenzie , A K , Callan , I R , Ainge , J A & O'Connor , A R 2018 , ' The discrimination ratio derived from novel object recognition tasks as a measure of recognition memory sensitivity, not bias ' , Scientific Reports , vol. 8 , 11579 . https://doi.org/10.1038/s41598-018-30030-7en
dc.identifier.issn2045-2322
dc.identifier.otherORCID: /0000-0002-7943-5183/work/47136383
dc.identifier.otherORCID: /0000-0002-0007-1533/work/60428120
dc.identifier.urihttps://hdl.handle.net/10023/15749
dc.descriptionThis work was supported by the Biotechnology and Biological Sciences Research Council UK (BBSRC) under the EastBio doctoral training program [grant number BB/J01446X/1].en
dc.description.abstractTranslational recognition memory research makes frequent use of the Novel Object Recognition (NOR) paradigm in which animals are simultaneously presented with one new and one old object. The preferential exploration of the new as compared to the old object produces a metric, the Discrimination Ratio (DR), assumed to represent recognition memory sensitivity. Human recognition memory studies typically assess performance using signal detection theory derived measures; sensitivity (d′) and bias (c). How DR relates to d′ and c and whether they measure the same underlying cognitive mechanism is, however, unknown. We investigated the correspondence between DR (eye-tracking-determined), d′ and c in a sample of 37 humans. We used dwell times during a visual paired comparison task (analogous to the NOR) to determine DR, and a separate single item recognition task to derive estimates of response sensitivity and bias. DR was found to be significantly positively correlated to sensitivity but not bias. Our findings confirm that DR corresponds to d′, the primary measure of recognition memory sensitivity in humans, and appears not to reflect bias. These findings are the first of their kind to suggest that animal researchers should be confident in interpreting the DR as an analogue of recognition memory sensitivity.
dc.format.extent1322520
dc.language.isoeng
dc.relation.ispartofScientific Reportsen
dc.subjectBF Psychologyen
dc.subjectNDASen
dc.subject.lccBFen
dc.titleThe discrimination ratio derived from novel object recognition tasks as a measure of recognition memory sensitivity, not biasen
dc.typeJournal articleen
dc.contributor.institutionUniversity of St Andrews. Institute of Behavioural and Neural Sciencesen
dc.contributor.institutionUniversity of St Andrews. School of Psychology and Neuroscienceen
dc.identifier.doi10.1038/s41598-018-30030-7
dc.description.statusPeer revieweden


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