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A comparison of copper and acid site zeolites for the production of nitric oxide for biomedical applications
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dc.contributor.author | Russell, Samantha E. | |
dc.contributor.author | González Carballo, Juan María | |
dc.contributor.author | Orellana-Tavra, Claudia | |
dc.contributor.author | Fairen-Jimenez, David | |
dc.contributor.author | Morris, Russell E. | |
dc.date.accessioned | 2018-03-01T00:33:08Z | |
dc.date.available | 2018-03-01T00:33:08Z | |
dc.date.issued | 2017-03-28 | |
dc.identifier | 250036129 | |
dc.identifier | c3777850-05ce-4da4-a35c-5861a031ecdc | |
dc.identifier | 85016158461 | |
dc.identifier | 000397882900017 | |
dc.identifier.citation | Russell , S E , González Carballo , J M , Orellana-Tavra , C , Fairen-Jimenez , D & Morris , R E 2017 , ' A comparison of copper and acid site zeolites for the production of nitric oxide for biomedical applications ' , Dalton Transactions , vol. 46 , no. 12 , pp. 3915-3920 . https://doi.org/10.1039/C7DT00195A | en |
dc.identifier.issn | 1477-9226 | |
dc.identifier.other | ORCID: /0000-0001-7809-0315/work/61622086 | |
dc.identifier.uri | https://hdl.handle.net/10023/12824 | |
dc.description | The authors would like to thank the Engineering and Physical Sciences Research Council, University of St Andrews, and CRITICAT Centre for Doctoral Training for financial support [Ph.D. studentship to SR; Grant code: EP/L016419/1]. C. A. O. thanks Becas Chile and the Cambridge Trust for funding. D. F.-J. thanks the Royal Society (UK) for funding through a University Research Fellowship. Thanks also go to Chevron for the sample of H-SSZ-13. | en |
dc.description.abstract | Copper-exchanged and acidic zeolites are shown to produce nitric oxide (NO) from a nitrite source in biologically active (nanomolar) concentrations. Four zeolites were studied; mordenite, ferrierite, ZSM-5 and SSZ-13, which had varying pore size, channel systems and Si/Al ratios. ZSM-5 and SSZ-13 produced the highest amounts of NO in both the copper and acid form. The high activity and regeneration of the copper active sites makes them good candidates for long-term NO production. Initial cytotoxicity tests have shown at least one of the copper zeolites (Cu-SSZ-13) to be biocompatible, highlighting the potential usage within biomedical applications. | |
dc.format.extent | 6 | |
dc.format.extent | 1413790 | |
dc.language.iso | eng | |
dc.relation.ispartof | Dalton Transactions | en |
dc.subject | QD Chemistry | en |
dc.subject | Inorganic Chemistry | en |
dc.subject | NDAS | en |
dc.subject.lcc | QD | en |
dc.title | A comparison of copper and acid site zeolites for the production of nitric oxide for biomedical applications | en |
dc.type | Journal article | en |
dc.contributor.sponsor | EPSRC | en |
dc.contributor.institution | University of St Andrews. School of Chemistry | en |
dc.contributor.institution | University of St Andrews. EaSTCHEM | en |
dc.identifier.doi | 10.1039/C7DT00195A | |
dc.description.status | Peer reviewed | en |
dc.date.embargoedUntil | 2018-02-28 | |
dc.identifier.grantnumber | EP/L016419/1 | en |
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