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dc.contributor.authorTrinkle-Mulcahy, Laura
dc.contributor.authorSleeman, Judith E.
dc.date.accessioned2017-09-23T23:32:21Z
dc.date.available2017-09-23T23:32:21Z
dc.date.issued2017
dc.identifier.citationTrinkle-Mulcahy , L & Sleeman , J E 2017 , ' The Cajal body and the nucleolus : “in a relationship” or “it's complicated”? ' , RNA Biology , vol. 14 , no. 6 , pp. 739-751 . https://doi.org/10.1080/15476286.2016.1236169en
dc.identifier.issn1547-6286
dc.identifier.otherPURE: 246305059
dc.identifier.otherPURE UUID: e4138f07-d675-4c6c-8ed2-a3ccbba3abc3
dc.identifier.otherRIS: urn:4994C28D788B7EE1D62A374F6C5D2CC9
dc.identifier.otherScopus: 84992062666
dc.identifier.otherWOS: 000406139300008
dc.identifier.urihttps://hdl.handle.net/10023/11728
dc.description.abstractFrom their initial identification as 'nucleolar accessory bodies' more than a century ago, the relationship between Cajal bodies and nucleoli has been a subject of interest and controversy. In this review, we seek to place recent developments in the understanding of the physical and functional relationships between the two structures in the context of historical observations. Biophysical models of nuclear body formation, the molecular nature of CB/nucleolus interactions and the increasing list of joint roles for CBs and nucleoli, predominantly in assembling ribonucleoprotein (RNP) complexes, are discussed.
dc.language.isoeng
dc.relation.ispartofRNA Biologyen
dc.rights© 2016, Taylor & Francis. This work is made available online in accordance with the publisher’s policies. This is the author created, accepted version manuscript following peer review and may differ slightly from the final published version. The final published version of this work is available at www.tandfonline.com / https://dx.doi.org/10.1080/15476286.2016.1236169en
dc.subjectNucleolusen
dc.subjectCajal bodyen
dc.subjectsnoRNPsen
dc.subjectsnRNPsen
dc.subjectNon-coding RNAsen
dc.subjectTelomeraseen
dc.subjectPhase separationen
dc.subjectNuclear structureen
dc.subjectNuclear bodiesen
dc.subjectCoilinen
dc.subjectQH301 Biologyen
dc.subjectRC0321 Neuroscience. Biological psychiatry. Neuropsychiatryen
dc.subject.lccQH301en
dc.subject.lccRC0321en
dc.titleThe Cajal body and the nucleolus : “in a relationship” or “it's complicated”?en
dc.typeJournal itemen
dc.description.versionPostprinten
dc.contributor.institutionUniversity of St Andrews. School of Biologyen
dc.contributor.institutionUniversity of St Andrews. Biomedical Sciences Research Complexen
dc.contributor.institutionUniversity of St Andrews. Institute of Behavioural and Neural Sciencesen
dc.identifier.doihttps://doi.org/10.1080/15476286.2016.1236169
dc.description.statusPeer revieweden
dc.date.embargoedUntil2017-09-23


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