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dc.contributor.authorPiksarv, Peeter
dc.contributor.authorMarti, Dominik
dc.contributor.authorLe, Tuan
dc.contributor.authorUnterhuber, Angelika
dc.contributor.authorForbes, Lindsey Helen
dc.contributor.authorAndrews, Melissa Renee
dc.contributor.authorStingl, Andreas
dc.contributor.authorDrexler, Wolfgang
dc.contributor.authorAndersen, Peter E.
dc.contributor.authorDholakia, Kishan
dc.date.accessioned2017-08-15T08:45:15Z
dc.date.available2017-08-15T08:45:15Z
dc.date.issued2017-05-03
dc.identifier249549002
dc.identifierfcef7251-e954-44de-99bc-04b97b95954d
dc.identifier85018753942
dc.identifier000400491700011
dc.identifier.citationPiksarv , P , Marti , D , Le , T , Unterhuber , A , Forbes , L H , Andrews , M R , Stingl , A , Drexler , W , Andersen , P E & Dholakia , K 2017 , ' Integrated single- and two-photon light sheet microscopy using accelerating beams ' , Scientific Reports , vol. 7 , 1435 . https://doi.org/10.1038/s41598-017-01543-4en
dc.identifier.issn2045-2322
dc.identifier.urihttps://hdl.handle.net/10023/11460
dc.descriptionThe authors thank the UK Engineering and Physical Sciences Research Council (grant EP/J01771/X) and the European Union project FAMOS (FP7 ICT, contract no. 317744) for funding. P.P. acknowledges funding by the Estonian Research Council (grants PUTJD8 and PUT369).en
dc.description.abstractWe demonstrate the first light sheet microscope using propagation invariant, accelerating Airy beams that operates both in single- and two-photon modes. The use of the Airy beam permits us to develop an ultra compact, high resolution light sheet system without beam scanning. In two-photon mode, an increase in the field of view over the use of a standard Gaussian beam by a factor of six is demonstrated. This implementation for light sheet microscopy opens up new possibilities across a wide range of biomedical applications, especially for the study of neuronal processes.
dc.format.extent2667686
dc.language.isoeng
dc.relation.ispartofScientific Reportsen
dc.subjectQC Physicsen
dc.subjectT Technologyen
dc.subjectDASen
dc.subject.lccQCen
dc.subject.lccTen
dc.titleIntegrated single- and two-photon light sheet microscopy using accelerating beamsen
dc.typeJournal articleen
dc.contributor.sponsorEPSRCen
dc.contributor.sponsorEuropean Commissionen
dc.contributor.institutionUniversity of St Andrews. School of Medicineen
dc.contributor.institutionUniversity of St Andrews. School of Physics and Astronomyen
dc.contributor.institutionUniversity of St Andrews. Biomedical Sciences Research Complexen
dc.identifier.doihttps://doi.org/10.1038/s41598-017-01543-4
dc.description.statusPeer revieweden
dc.identifier.urlhttps://www.nature.com/articles/s41598-017-01543-4#supplementary-informationen
dc.identifier.grantnumberEP/J01771X/1en
dc.identifier.grantnumber317744en


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