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Integrated single- and two-photon light sheet microscopy using accelerating beams
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dc.contributor.author | Piksarv, Peeter | |
dc.contributor.author | Marti, Dominik | |
dc.contributor.author | Le, Tuan | |
dc.contributor.author | Unterhuber, Angelika | |
dc.contributor.author | Forbes, Lindsey Helen | |
dc.contributor.author | Andrews, Melissa Renee | |
dc.contributor.author | Stingl, Andreas | |
dc.contributor.author | Drexler, Wolfgang | |
dc.contributor.author | Andersen, Peter E. | |
dc.contributor.author | Dholakia, Kishan | |
dc.date.accessioned | 2017-08-15T08:45:15Z | |
dc.date.available | 2017-08-15T08:45:15Z | |
dc.date.issued | 2017-05-03 | |
dc.identifier | 249549002 | |
dc.identifier | fcef7251-e954-44de-99bc-04b97b95954d | |
dc.identifier | 85018753942 | |
dc.identifier | 000400491700011 | |
dc.identifier.citation | Piksarv , P , Marti , D , Le , T , Unterhuber , A , Forbes , L H , Andrews , M R , Stingl , A , Drexler , W , Andersen , P E & Dholakia , K 2017 , ' Integrated single- and two-photon light sheet microscopy using accelerating beams ' , Scientific Reports , vol. 7 , 1435 . https://doi.org/10.1038/s41598-017-01543-4 | en |
dc.identifier.issn | 2045-2322 | |
dc.identifier.uri | https://hdl.handle.net/10023/11460 | |
dc.description | The authors thank the UK Engineering and Physical Sciences Research Council (grant EP/J01771/X) and the European Union project FAMOS (FP7 ICT, contract no. 317744) for funding. P.P. acknowledges funding by the Estonian Research Council (grants PUTJD8 and PUT369). | en |
dc.description.abstract | We demonstrate the first light sheet microscope using propagation invariant, accelerating Airy beams that operates both in single- and two-photon modes. The use of the Airy beam permits us to develop an ultra compact, high resolution light sheet system without beam scanning. In two-photon mode, an increase in the field of view over the use of a standard Gaussian beam by a factor of six is demonstrated. This implementation for light sheet microscopy opens up new possibilities across a wide range of biomedical applications, especially for the study of neuronal processes. | |
dc.format.extent | 2667686 | |
dc.language.iso | eng | |
dc.relation.ispartof | Scientific Reports | en |
dc.subject | QC Physics | en |
dc.subject | T Technology | en |
dc.subject | DAS | en |
dc.subject.lcc | QC | en |
dc.subject.lcc | T | en |
dc.title | Integrated single- and two-photon light sheet microscopy using accelerating beams | en |
dc.type | Journal article | en |
dc.contributor.sponsor | EPSRC | en |
dc.contributor.sponsor | European Commission | en |
dc.contributor.institution | University of St Andrews. School of Medicine | en |
dc.contributor.institution | University of St Andrews. School of Physics and Astronomy | en |
dc.contributor.institution | University of St Andrews. Biomedical Sciences Research Complex | en |
dc.identifier.doi | https://doi.org/10.1038/s41598-017-01543-4 | |
dc.description.status | Peer reviewed | en |
dc.identifier.url | https://www.nature.com/articles/s41598-017-01543-4#supplementary-information | en |
dc.identifier.grantnumber | EP/J01771X/1 | en |
dc.identifier.grantnumber | 317744 | en |
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