Fertility preservation in pre-pubertal girls with cancer : the role of ovarian tissue cryopreservation
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With increasing numbers of survivors of cancer in young people future fertility and ovarian function are important considerations that should be discussed before treatment commences. Some young people, by nature of the treatment they will receive, are at high risk of premature ovarian insufficiency and infertility. For them, ovarian tissue cryopreservation (OTC) is one approach to fertility preservation that remains both invasive and for young patients experimental. There are important ethical and consent issues that need to be explored and accepted before OTC can be considered established in children with cancer. In this review we have discussed a framework for patient selection which has been shown to be effective in identifying those patients at high risk of premature ovarian insufficiency (POI) and who can be offered OTC safely.
Wallace , W H B , Kelsey , T W & Anderson , R A 2016 , ' Fertility preservation in pre-pubertal girls with cancer : the role of ovarian tissue cryopreservation ' Fertility and Sterility , vol 105 , no. 1 , pp. 6-12 . DOI: 10.1016/j.fertnstert.2015.11.041
Fertility and Sterility
© 2016, Publisher / the Author(s). This work is made available online in accordance with the publisher’s policies. This is the author created, accepted version manuscript following peer review and may differ slightly from the final published version. The final published version of this work is available at https://dx.doi.org/10.1016/j.fertnstert.2015.11.041
Copyright © 2016 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
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