Show simple item record

Files in this item

Thumbnail

Item metadata

dc.contributor.authorKosikova, Tamara
dc.contributor.authorMackenzie, Harry
dc.contributor.authorPhilp, Douglas
dc.date.accessioned2016-12-23T00:32:31Z
dc.date.available2016-12-23T00:32:31Z
dc.date.issued2016-01-26
dc.identifier.citationKosikova , T , Mackenzie , H & Philp , D 2016 , ' Probing the limits of selectivity in a recognition-mediated reaction network embedded within a dynamic covalent library ' , Chemistry - A European Journal , vol. 22 , no. 5 , pp. 1831–1839 . https://doi.org/10.1002/chem.201503740en
dc.identifier.issn0947-6539
dc.identifier.otherPURE: 234637271
dc.identifier.otherPURE UUID: d02795db-dc74-45bb-bdd5-04e27bd4da66
dc.identifier.otherScopus: 84958056848
dc.identifier.otherORCID: /0000-0002-9198-4302/work/56639256
dc.identifier.otherWOS: 000368924100037
dc.identifier.urihttp://hdl.handle.net/10023/10010
dc.descriptionThis work was supported by the award of a Postgraduate Studentship from EPSRC (EP/K503162/1) to TK.en
dc.description.abstractTwo recognition-mediated reaction processes operating through a reactive binary complex drive resolution of a 24-component dynamic covalent library, assembled from individual aldehydes and nucleophiles. The effectiveness of the library resolution and selective amplification of one recognition-enabled species over another is limited by the difference in the rates of the recognition-mediated reactive processes and strength of the recognition processes employed in the dynamic system.
dc.language.isoeng
dc.relation.ispartofChemistry - A European Journalen
dc.rights© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. This work is made available online in accordance with the publisher’s policies. This is the author created, accepted version manuscript following peer review and may differ slightly from the final published version. The final published version of this work is available at https://dx.doi.org/10.1002/chem.201503740en
dc.subjectCombinatorial chemistryen
dc.subjectCycloaddition reactionen
dc.subjectKineticsen
dc.subjectMolecular recognitionen
dc.subjectNMR spectroscopen
dc.subjectQD Chemistryen
dc.subjectDASen
dc.subject.lccQDen
dc.titleProbing the limits of selectivity in a recognition-mediated reaction network embedded within a dynamic covalent libraryen
dc.typeJournal articleen
dc.description.versionPostprinten
dc.contributor.institutionUniversity of St Andrews.School of Chemistryen
dc.contributor.institutionUniversity of St Andrews.EaSTCHEMen
dc.contributor.institutionUniversity of St Andrews.Biomedical Sciences Research Complexen
dc.identifier.doihttps://doi.org/10.1002/chem.201503740
dc.description.statusPeer revieweden
dc.date.embargoedUntil2016-12-22


This item appears in the following Collection(s)

Show simple item record