Probing the limits of selectivity in a recognition-mediated reaction network embedded within a dynamic covalent library
Abstract
Two recognition-mediated reaction processes operating through a reactive binary complex drive resolution of a 24-component dynamic covalent library, assembled from individual aldehydes and nucleophiles. The effectiveness of the library resolution and selective amplification of one recognition-enabled species over another is limited by the difference in the rates of the recognition-mediated reactive processes and strength of the recognition processes employed in the dynamic system.
Citation
Kosikova , T , Mackenzie , H & Philp , D 2016 , ' Probing the limits of selectivity in a recognition-mediated reaction network embedded within a dynamic covalent library ' , Chemistry - A European Journal , vol. 22 , no. 5 , pp. 1831–1839 . https://doi.org/10.1002/chem.201503740
Publication
Chemistry - A European Journal
Status
Peer reviewed
ISSN
0947-6539Type
Journal article
Rights
© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. This work is made available online in accordance with the publisher’s policies. This is the author created, accepted version manuscript following peer review and may differ slightly from the final published version. The final published version of this work is available at https://dx.doi.org/10.1002/chem.201503740
Description
This work was supported by the award of a Postgraduate Studentship from EPSRC (EP/K503162/1) to TK.Collections
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