Light-stable silver N-Heterocyclic carbene catalysts for the alkynylation of ketones in air

N-Heterocyclic carbene (NHC) silver(I) complexes were efficiently employed in the alkynylation of ketones. These cationic complexes were found highly active and efficient under mild conditions without the need of additive, and in air. The mechanism of this transformation was investigated. Experiments suggest the formation of a silver-acetylide key intermediate and the release of one ligand from the silver centre enabling the transformation.

Citation

Lazreg , F , Lesieur , M , Sansom , A J & Cazin , C S J 2015 , ' Light-stable silver N -Heterocyclic carbene catalysts for the alkynylation of ketones in air ' , ChemCatChem , vol. In press . https://doi.org/10.1002/cctc.201500869

Publication

ChemCatChem

Status

Peer reviewed

DOI

https://doi.org/10.1002/cctc.201500869

ISSN

1867-3880

Type

Journal article

Rights

© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. This work is made available online in accordance with the publisher’s policies. This is the author created, accepted version manuscript following peer review and may differ slightly from the final published version. The final published version of this work is available at https://dx.doi.org/10.1002/cctc.201500869

Description

The authors gratefully acknowledge the Royal Society (University Research Fellowship to C.S.J.C) for funding.