Synthesis of (R)-Lactic Acid and (2R,5R)-2-tert-Butyl-5-methyl-1,3-dioxolan-4-one
Abstract
A convenient procedure for the synthesis of very expensive (R)-lactic acid from relatively inexpensive (R)-alanine is described. Its subsequent conversion into a chiral dioxolanone can be carried out by using an inexpensive pivalaldehyde–tert-butanol mixture.
Citation
Aitken , R A , Meehan , A & Power , L A 2015 , ' Synthesis of (R)-Lactic Acid and (2R,5R)-2-tert-Butyl-5-methyl-1,3-dioxolan-4-one ' Synthesis , vol 47 , no. 11 , pp. 1557-1559 . DOI: 10.1055/s-0034-1380511
Version
Postprint
Publication
Synthesis
Status
Peer reviewed
ISSN
0039-7881Type
Journal article
Rights
© Georg Thieme Verlag Stuttgart - New York. This work is made available online in accordance with the publisher’s policies. This is the author created, accepted version manuscript following peer review and may differ slightly from the final published version. The final published version of this work is available at http://dx.doi.org/10.1055/s-0034-1380511
Collections
Items in the St Andrews Research Repository are protected by copyright, with all rights reserved, unless otherwise indicated.