A straightforward metal-free synthesis of 2-substituted thiazolines in air
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A base-catalysed procedure for the synthesis of 2-substituted thiazolines from nitriles and cysteamine hydrochloride under solvent-free conditions is presented. This straightforward approach allows high conversion for a broad range of nitriles and an easy isolation of the desired products.
Trose , M , Lazreg , F , Lesieur , M & Cazin , C S J 2015 , ' A straightforward metal-free synthesis of 2-substituted thiazolines in air ' , Green Chemistry , vol. 17 , no. 5 , pp. 3090-3092 . https://doi.org/10.1039/c5gc00286a
Copyright 2015 the Authors. This work is made available online in accordance with the publisher’s policies. This is the author created, accepted version manuscript following peer review and may differ slightly from the final published version. The final published version of this work is available at: https://dx.doi.org/10.1039/C5GC00286A
DescriptionThe authors are grateful to the Royal Society (University Research Fellowship to CSJC) for financial support.
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