Accurate extraction of nanometer distances in multimers by pulse EPR
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Pulse electron paramagnetic resonance (EPR) is gaining increasing importance in structural biology. The PELDOR (pulsed electron-electron double resonance) method allows extracting distance information on the nanometer scale. Here, we demonstrate the efficient extraction of distances from multimeric systems such as membrane embedded ion channels where data analysis is commonly hindered by multi-spin effects.
Valera , S , Ackermann , K , Pliotas , C , Huang , H , Naismith , J H & Bode , B E 2016 , ' Accurate extraction of nanometer distances in multimers by pulse EPR ' Chemistry - A European Journal , vol 22 , no. 14 , pp. 4700–4703 . DOI: 10.1002/chem.201505143
Chemistry - A European Journal
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