Novel ether and thioether macrocycles from phthalaldehyde
Abstract
By reaction of phthalaldehyde (benzene-1,2-dicarbaldehyde) with ethane-1,2-diol or 2-mercaptoethanol, macrocycles containing respectively 14- and 12-membered polyether/thioether rings were obtained in low but reproducible yield and their structures confirmed by X-ray diffraction. The simple compounds (2-vinylphenyl)oxirane and 2-oxiranylbenzaldehyde have also been prepared and characterised for the first time.
Citation
Aitken , R A , Hauduc , C , McLennan , R S , Slawin , A M Z & Wilson , H S 2015 , ' Novel ether and thioether macrocycles from phthalaldehyde ' , Tetrahedron Letters , vol. 56 , no. 15 , pp. 1937-1940 . https://doi.org/10.1016/j.tetlet.2015.02.003
Publication
Tetrahedron Letters
Status
Peer reviewed
ISSN
0040-4039Type
Journal article
Collections
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