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Stereoselective gold(I)-catalyzed intermolecular hydroalkoxlation of alkynes
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dc.contributor.author | Veenboer, Richard Marinus Petrus | |
dc.contributor.author | Dupuy, Stephanie | |
dc.contributor.author | Nolan, Steven Patrick | |
dc.date.accessioned | 2016-01-21T00:12:27Z | |
dc.date.available | 2016-01-21T00:12:27Z | |
dc.date.issued | 2015-02-06 | |
dc.identifier | 168875397 | |
dc.identifier | b4b792ec-f3e2-46a1-9688-bee8a58b64eb | |
dc.identifier | 84922728976 | |
dc.identifier | 000349275300092 | |
dc.identifier.citation | Veenboer , R M P , Dupuy , S & Nolan , S P 2015 , ' Stereoselective gold(I)-catalyzed intermolecular hydroalkoxlation of alkynes ' , ACS Catalysis , vol. 5 , no. 2 , pp. 1330-1334 . https://doi.org/10.1021/cs501976s | en |
dc.identifier.issn | 2155-5435 | |
dc.identifier.uri | https://hdl.handle.net/10023/8050 | |
dc.description | The EPSRC and ERC are gratefully acknowledged for support. | en |
dc.description.abstract | We report the use of cationic gold complexes [Au(NHC)(CH3CN)][BF4] and [{Au(NHC)}2(μ-OH)][BF4] (NHC = N-heterocyclic carbene) as highly active catalysts in the solvent-free hydroalkoxylation of internal alkynes using primary and secondary alcohols. Using this simple protocol, a broad range of (Z)-vinyl ethers were obtained in excellent yields and high stereoselectivities. The methodology allows for the use of catalyst loadings as low as 200 ppm for the addition of primary alcohols to internal alkynes (TON = 35 000, TOF = 2188 h-1). | |
dc.format.extent | 5 | |
dc.format.extent | 648560 | |
dc.language.iso | eng | |
dc.relation.ispartof | ACS Catalysis | en |
dc.subject | Gold | en |
dc.subject | Hydroalkoxylation | en |
dc.subject | Alkynes | en |
dc.subject | Vinyl ethers | en |
dc.subject | Solvent-free | en |
dc.subject | QD Chemistry | en |
dc.subject | NDAS | en |
dc.subject.lcc | QD | en |
dc.title | Stereoselective gold(I)-catalyzed intermolecular hydroalkoxlation of alkynes | en |
dc.type | Journal article | en |
dc.contributor.institution | University of St Andrews. School of Chemistry | en |
dc.contributor.institution | University of St Andrews. EaSTCHEM | en |
dc.identifier.doi | 10.1021/cs501976s | |
dc.description.status | Peer reviewed | en |
dc.date.embargoedUntil | 2016-01-21 | |
dc.identifier.url | http://pubs.acs.org/doi/suppl/10.1021/cs501976s | en |
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