Facile synthesis and structure of novel 2,5-disubstituted 1,3,4-selenadiazoles
Abstract
The reaction of hydrazide with carbonyl chloride in the presence of sodium carbonates leads to the corresponding 1,2-diacylhydrazines [ 1a – t , R1C(O)NHNHC(O)R2, R1 = aryl, R2 = aryl or alkyl] in moderate to excellent yield (57–90 %). The latter reacts with 2,4-diphenyl-1,3-diselenadiphosphetane-2,4-diselenide (Woollins' reagent, WR ) in refluxing toluene to give a series of new 2,5-disubstituted 1,3,4-selenadiazoles ( 2a – t , 51–99 % yield). All compounds were characterized spectroscopically and six compounds were characterized crystallographically.
Citation
Hua , G , Li , Y , Fuller , A , Slawin , A M Z & Woollins , J D 2009 , ' Facile synthesis and structure of novel 2,5-disubstituted 1,3,4-selenadiazoles ' , European Journal of Organic Chemistry , vol. 2009 , no. 10 , pp. 1612-1618 . https://doi.org/10.1002/ejoc.200900013
Publication
European Journal of Organic Chemistry
Status
Peer reviewed
ISSN
1434-193XType
Journal article
Description
This work is funded by EPSRC UKCollections
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