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dc.contributor.authorParker, D. J.
dc.contributor.authorVesala, L.
dc.contributor.authorRitchie, M. G.
dc.contributor.authorLaiho, A.
dc.contributor.authorHoikkala, A.
dc.contributor.authorKankare, M.
dc.date.accessioned2016-01-13T15:40:05Z
dc.date.available2016-01-13T15:40:05Z
dc.date.issued2015-07
dc.identifier.citationParker , D J , Vesala , L , Ritchie , M G , Laiho , A , Hoikkala , A & Kankare , M 2015 , ' How consistent are the transcriptome changes associated with cold acclimation in two species of the Drosophila virilis group? ' , Heredity , vol. 115 , no. 1 , pp. 13-21 . https://doi.org/10.1038/hdy.2015.6en
dc.identifier.issn0018-067X
dc.identifier.otherPURE: 200222428
dc.identifier.otherPURE UUID: 54244db5-c9a4-470a-a4ed-6203efd8e842
dc.identifier.otherWOS: 000356024900003
dc.identifier.otherScopus: 84930868700
dc.identifier.otherORCID: /0000-0001-7913-8675/work/46761147
dc.identifier.otherWOS: 000356024900003
dc.identifier.urihttp://hdl.handle.net/10023/8014
dc.descriptionThis work was financially support by a Marie Curie Initial Training Network grant, “Understanding the evolutionary origin of biological diversity” (ITN-2008–213780 SPECIATION), grants from the Academy of Finland to A.H. (project 132619) and M.K. (projects 268214 and 272927), a grant from NERC, UK to M.G.R. (grant NE/J020818/1), and NERC, UK PhD studentship to D.J.P. (NE/I528634/1).en
dc.description.abstractFor many organisms the ability to cold acclimate with the onset of seasonal cold has major implications for their fitness. In insects, where this ability is widespread, the physiological changes associated with increased cold tolerance have been well studied. Despite this, little work has been done to trace changes in gene expression during cold acclimation that lead to an increase in cold tolerance. We used an RNA-Seq approach to investigate this in two species of the Drosophila virilis group. We found that the majority of genes that are differentially expressed during cold acclimation differ between the two species. Despite this, the biological processes associated with the differentially expressed genes were broadly similar in the two species. These included: metabolism, cell membrane composition, and circadian rhythms, which are largely consistent with previous work on cold acclimation/cold tolerance. In addition, we also found evidence of the involvement of the rhodopsin pathway in cold acclimation, a pathway that has been recently linked to thermotaxis. Interestingly, we found no evidence of differential expression of stress genes implying that long-term cold acclimation and short-term stress response may have a different physiological basis.
dc.format.extent9
dc.language.isoeng
dc.relation.ispartofHeredityen
dc.rights© 2015, Publisher / the Author(s). This work is made available online in accordance with the publisher’s policies. This is the author created, accepted version manuscript following peer review and may differ slightly from the final published version. The final published version of this work is available at www.nature.com / https://dx.doi.org/10.1038/hdy.2015.6en
dc.subjectDifferential expression analysisen
dc.subjectNorthern house mosquitoen
dc.subjectLarge gene listsen
dc.subjectBiological-membranesen
dc.subjectStress toleranceen
dc.subjectCulex-pipiensen
dc.subjectChill-comaen
dc.subjectTemperatureen
dc.subjectMelanogasteren
dc.subjectMyoinositolen
dc.subjectQH301 Biologyen
dc.subject.lccQH301en
dc.titleHow consistent are the transcriptome changes associated with cold acclimation in two species of the Drosophila virilis group?en
dc.typeJournal articleen
dc.contributor.sponsorNERCen
dc.contributor.sponsorNERCen
dc.description.versionPostprinten
dc.contributor.institutionUniversity of St Andrews. School of Biologyen
dc.contributor.institutionUniversity of St Andrews. Centre for Biological Diversityen
dc.contributor.institutionUniversity of St Andrews. Institute of Behavioural and Neural Sciencesen
dc.identifier.doihttps://doi.org/10.1038/hdy.2015.6
dc.description.statusPeer revieweden
dc.identifier.grantnumberNE/E015255/1en
dc.identifier.grantnumberNE/J020818/1en


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