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dc.contributor.authorKillip, M.J.
dc.contributor.authorFodor, E.
dc.contributor.authorRandall, R.E.
dc.identifier.citationKillip , M J , Fodor , E & Randall , R E 2015 , ' Influenza virus activation of the interferon system ' , Virus Research .
dc.identifier.otherPURE: 173613926
dc.identifier.otherPURE UUID: dc05a3ab-b91f-432c-b7e3-cefd711abe1a
dc.identifier.otherScopus: 84959511733
dc.identifier.otherORCID: /0000-0002-9304-6678/work/60427012
dc.identifier.otherWOS: 000364886600003
dc.descriptionThis study was supported by the Wellcome Trust (grant number 087751/A/08/Z) and the Medical Research Council (grant number G0700848).en
dc.description.abstractThe host interferon (IFN) response represents one of the first barriers that influenza viruses must surmount in order to establish an infection. Many advances have been made in recent years in understanding the interactions between influenza viruses and the interferon system. In this review, we summarise recent work regarding activation of the type I IFN response by influenza viruses, including attempts to identify the viral RNA responsible for IFN induction, the stage of the virus life cycle at which it is generated and the role of defective viruses in this process.
dc.relation.ispartofVirus Researchen
dc.rights© 2015 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license (
dc.subjectInfluenza virusesen
dc.subjectInnate immunityen
dc.subjectQR355 Virologyen
dc.subjectQR180 Immunologyen
dc.titleInfluenza virus activation of the interferon systemen
dc.typeJournal articleen
dc.description.versionPublisher PDFen
dc.contributor.institutionUniversity of St Andrews. School of Biologyen
dc.contributor.institutionUniversity of St Andrews. Biomedical Sciences Research Complexen
dc.description.statusPeer revieweden

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