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Influenza virus activation of the interferon system

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dc.contributor.authorKillip, M.J.
dc.contributor.authorFodor, E.
dc.contributor.authorRandall, R.E.
dc.date.accessioned2015-03-10T15:01:02Z
dc.date.available2015-03-10T15:01:02Z
dc.date.issued2015
dc.identifier173613926
dc.identifierdc05a3ab-b91f-432c-b7e3-cefd711abe1a
dc.identifier84959511733
dc.identifier000364886600003
dc.identifier.citationKillip , M J , Fodor , E & Randall , R E 2015 , ' Influenza virus activation of the interferon system ' , Virus Research . https://doi.org/10.1016/j.virusres.2015.02.003en
dc.identifier.issn0168-1702
dc.identifier.otherORCID: /0000-0002-9304-6678/work/60427012
dc.identifier.urihttps://hdl.handle.net/10023/6200
dc.descriptionThis study was supported by the Wellcome Trust (grant number 087751/A/08/Z) and the Medical Research Council (grant number G0700848).en
dc.description.abstractThe host interferon (IFN) response represents one of the first barriers that influenza viruses must surmount in order to establish an infection. Many advances have been made in recent years in understanding the interactions between influenza viruses and the interferon system. In this review, we summarise recent work regarding activation of the type I IFN response by influenza viruses, including attempts to identify the viral RNA responsible for IFN induction, the stage of the virus life cycle at which it is generated and the role of defective viruses in this process.
dc.format.extent1576856
dc.language.isoeng
dc.relation.ispartofVirus Researchen
dc.subjectInfluenza virusesen
dc.subjectInnate immunityen
dc.subjectInterferonen
dc.subjectRIG-Ien
dc.subjectQR355 Virologyen
dc.subjectQR180 Immunologyen
dc.subjectT-NDASen
dc.subject.lccQR355en
dc.subject.lccQR180en
dc.titleInfluenza virus activation of the interferon systemen
dc.typeJournal articleen
dc.contributor.institutionUniversity of St Andrews. School of Biologyen
dc.contributor.institutionUniversity of St Andrews. Biomedical Sciences Research Complexen
dc.identifier.doihttps://doi.org/10.1016/j.virusres.2015.02.003
dc.description.statusPeer revieweden


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