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Electrical conductivity measurement in Thiel-embalmed tissue model : relevance to radiofrequency ablation
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dc.contributor.author | Wang, Z. | |
dc.contributor.author | Luo, H. | |
dc.contributor.author | Nick, M. | |
dc.contributor.author | Gueorguieva, M. | |
dc.contributor.author | Andre, P. | |
dc.contributor.author | Baker, R.T. | |
dc.contributor.author | McLean, D. | |
dc.contributor.author | Brown, S. | |
dc.contributor.author | Cuschieri, A. | |
dc.date.accessioned | 2015-02-24T16:31:01Z | |
dc.date.available | 2015-02-24T16:31:01Z | |
dc.date.issued | 2014-07-31 | |
dc.identifier.citation | Wang , Z , Luo , H , Nick , M , Gueorguieva , M , Andre , P , Baker , R T , McLean , D , Brown , S & Cuschieri , A 2014 , ' Electrical conductivity measurement in Thiel-embalmed tissue model : relevance to radiofrequency ablation ' , Electronics Letters , vol. 50 , no. 16 , pp. 1125-1127 . https://doi.org/10.1049/el.2014.1934 | en |
dc.identifier.issn | 0013-5194 | |
dc.identifier.other | PURE: 148650251 | |
dc.identifier.other | PURE UUID: e6956052-d0eb-47e1-85fb-e5e6e327c750 | |
dc.identifier.other | Scopus: 84905254834 | |
dc.identifier.other | ORCID: /0000-0002-3304-3280/work/59464818 | |
dc.identifier.other | WOS: 000341023800012 | |
dc.identifier.uri | https://hdl.handle.net/10023/6141 | |
dc.description | PA gratefully acknowledges SUPA for funding his Advanced Research Fellowship. | en |
dc.description.abstract | Thiel-embalmed human cadaveric specimens are used widely for biomedical scientific investigation. This Letter reports electrical impedance measurements of Thiel-embalming solutions from 1 Hz to 32 MHz. Compared with other solutions studied, Thiel solution has the lowest impedance throughout the test spectrum. The electrical conductivity of a Thiel-embalmed liver sample exhibited a relatively flat frequency response from 100 to 500 kHz, which is the frequency range used for electro-surgery and radiofrequency tumour ablation (RFA). It measured 5 Sm-1 compared with 0.22 Sm-1 obtained from ex-vivo fresh pig liver. Using finite element modelling and experimental evaluation, the ablation zone obtained from the Thiel-embalmed liver sample was extremely small due to its much higher conductivity. Hence, it is concluded that Thiel-embalmed tissue cannot be used as a reliable model for RFA evaluation. | |
dc.format.extent | 3 | |
dc.language.iso | eng | |
dc.relation.ispartof | Electronics Letters | en |
dc.rights | © 2014. The Institution of Engineering and Technology. This paper is a postprint of a paper submitted to and accepted for publication in Electronics Letters and is subject to Institution of Engineering and Technology Copyright. The copy of record is available at IET Digital Library | en |
dc.subject | QD Chemistry | en |
dc.subject | R Medicine | en |
dc.subject.lcc | QD | en |
dc.subject.lcc | R | en |
dc.title | Electrical conductivity measurement in Thiel-embalmed tissue model : relevance to radiofrequency ablation | en |
dc.type | Journal article | en |
dc.description.version | Postprint | en |
dc.contributor.institution | University of St Andrews. School of Physics and Astronomy | en |
dc.contributor.institution | University of St Andrews. School of Chemistry | en |
dc.contributor.institution | University of St Andrews. St Andrews Sustainability Institute | en |
dc.contributor.institution | University of St Andrews. EaSTCHEM | en |
dc.contributor.institution | University of St Andrews. School of Medicine | en |
dc.identifier.doi | https://doi.org/10.1049/el.2014.1934 | |
dc.description.status | Peer reviewed | en |
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