A new synthetic route to p-methoxy-2,6-disubstituted anilines and their conversion into N-heterocyclic carbene precursors
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The development of new N-heterocyclic carbenes (NHC) is a key feature in this now mainstream research area to access novel chemical properties and reactivity that are essential for the discovery of original applications. Up to now, only a few reliable methods have proven suitable for the preparation of methoxylated anilines to ultimately access methoxylated NHC. We are pleased to report here a straightforward and scalable approach to address this matter.
Meiries , S M B & Nolan , S P 2014 , ' A new synthetic route to p -methoxy-2,6-disubstituted anilines and their conversion into N-heterocyclic carbene precursors ' , Synlett , vol. 25 , no. 3 , pp. 393-398 . https://doi.org/10.1055/s-0033-1340105
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