Three closely related dibenzazepine carboxylic acids : hydrogen-bonded aggregation in one, two and three dimensions
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In the structure of (6R*,11R*)-5-acetyl-11-ethyl-6,11-dihydro-5H-dibenzo[b,e]azepine-6-carboxylic acid, C19H19NO3, (I), the molecules are linked into sheets by a combination of O-H...O and C-H...O hydrogen bonds; in the structure of the monomethyl analogue (6RS,11SR)-5-acetyl-11-ethyl-2-methyl-6,11-dihydro-5H-dibenzo[b,e]azepine-6-carboxylic acid, C20H21NO3, (II), the molecules are linked into simple C(7) chains by O-H...O hydrogen bonds; and in the structure of the dimethyl analogue (6RS,11SR)-5-acetyl-11-ethyl-1,3-dimethyl-6,11-dihydro-5H-dibenzo[b,e]azepine-6-carboxylic acid, C21H23NO3, (III), a combination of O-H...O, C-H...O and C-H...π(arene) hydrogen bonds links the molecules into a three-dimensional framework structure. None of these structures exhibits the R22(8) dimer motif characteristic of simple carboxylic acids.
Sanabria , C M , Palma , A , Cobo , J & Glidewell , C 2014 , ' Three closely related dibenzazepine carboxylic acids : hydrogen-bonded aggregation in one, two and three dimensions ' Acta Crystallographica Section C: Crystal Structure Communications , vol 70 , no. 3 , pp. 332-337 . DOI: 10.1107/S2053229614003568
Acta Crystallographica Section C: Crystal Structure Communications
Copyright 2014 International Union of Crystallography
DescriptionThe authors thank the Centro de Instrumentacio´n Cientı´- fico-Te´ cnica of the Universidad de Jae´n and the staff for the data collection. AP and CMS thank Colciencias for financial support (grant No. 1102-521-28229). JC thanks the Consejerı´a de Innovacio´ n, Ciencia y Empresa (Junta de Andalucı´a, Spain) and the Universidad de Jae´n for financial support.
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