Medicine Theses: Recent submissions
Now showing items 66-70 of 143
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Phenotypic discrimination of Mycobacterium tuberculosis by Raman spectroscopy
(University of St Andrews, 2018-06-29) - ThesisTB remains a major health issue worldwide causing around 1.5 deaths each year. The recent phase III clinical trials of shortened TB treatment failed to show superiority compared to the current regimen and this mainly because ... -
Zebrafish as a model to study genes associated with neurodevelopmental disorders
(University of St Andrews, 2018-12-06) - ThesisDyslexia is a neurodevelopmental disorder that affects between 5% and 12% of school-aged children. Individuals with dyslexia have difficulties in learning to read despite normal IQ levels and adequate socio-economical and ... -
Towards light sheet microscopy-based high throughput imaging and CRISPR optogenetics
(University of St Andrews, 2018-12-06) - ThesisHigh Throughput Imaging (HTI) has an important role in the High Throughput/Content Screening process (HTS/HCS). It is widely used in the drug discovery process and in a wide range of other applications including studies ... -
Investigating the role of Zn²⁺ in regulating the function of intracellular Ca²⁺-release channels
(University of St Andrews, 2018-12-06) - ThesisThe tightly regulated openings of the cardiac ryanodine receptor (RyR2) help to ensure that intracellular Ca²⁺- release from the sarcoplasmic reticulum (SR) can only occur when heart contractions are required. Usually ... -
Transforming clinical mycobacteriology with modern molecular methodology
(University of St Andrews, 2018) - ThesisWhole genome sequencing (WGS) is an attractive approach for mycobacteria diagnosis and epidemiological studies. It provides the potential for a rapid method that produces detailed information and could theoretically be ...