Medicine Research: Recent submissions
Now showing items 26-30 of 59
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Using 'dead or dependent' as an outcome measure in clinical trials in Parkinson's disease
(2015-02) - Journal articleBACKGROUND: Simple, robust, sensitive and clinically meaningful outcome measures are required for neuroprotective trials in Parkinson's disease (PD). We explored the feasibility of a composite binary outcome measure, 'dead ... -
Equitable tuberculosis care in the North West of England : analysis of tuberculosis cohort review data
(2016-06-01) - Journal articleBACKGROUND: In the United Kingdom, tuberculosis (TB) predominantly affects the most deprived populations, yet the extent to which deprivation affects TB care outcomes is unknown. METHODS: Since 2011, the North West TB ... -
Kinetics of Mycobacterium tuberculosis-specific IFN-γ responses and sputum bacillary clearance in HIV-infected adults during treatment of pulmonary tuberculosis
(2015-07-01) - Journal articleIn HIV-uninfected adults with pulmonary tuberculosis (TB), anti-TB treatment is associated with changes in Mycobacterium tuberculosis (Mtb)-specific immune responses, which correlate with sputum bacillary load. It is unclear ... -
Vitamin D deficiency in Malawian adults with pulmonary tuberculosis : risk factors and treatment outcomes
(2015-08-01) - Journal articleSETTING: Vitamin D deficiency is common in African adults with tuberculosis (TB), and may be exacerbated by the metabolic effects of anti-tuberculosis drugs and antiretroviral therapy (ART). It is unclear whether vitamin ... -
Discordance between clinical and immunological ART eligibility criteria for children in Malawi
(2014-09-22) - Journal articleBackground Since May 2014, all HIV positive children aged less than five years in Malawi are eligible for ART. For children older than five years they are eligible if they are in WHO stage III/IV, if stage I/II, if their ...