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dc.contributor.authorSchumann, G.
dc.contributor.authorBinder, E.B.
dc.contributor.authorHolte, A.
dc.contributor.authorde Kloet, E.R.
dc.contributor.authorOedegaard, K.J.
dc.contributor.authorRobbins, T.W.
dc.contributor.authorWalker-Tilley, T.R.
dc.contributor.authorBitter, I.
dc.contributor.authorBrown, V.J.
dc.contributor.authorBuitelaar, J.
dc.contributor.authorCiccocioppo, R.
dc.contributor.authorCools, R.
dc.contributor.authorEscera, C.
dc.contributor.authorFleischhacker, W.
dc.contributor.authorFlor, H.
dc.contributor.authorFrith, C.D.
dc.contributor.authorHeinz, A.
dc.contributor.authorJohnsen, E.
dc.contributor.authorKirschbaum, C.
dc.contributor.authorKlingberg, T.
dc.contributor.authorLesch, K.-P.
dc.contributor.authorLewis, S.
dc.contributor.authorMaier, W.
dc.contributor.authorMann, Karl
dc.contributor.authorMartinot, J.-L.
dc.contributor.authorMeyer-Lindenberg, A.
dc.contributor.authorMüller, C.P.
dc.contributor.authorMüller, W.E.
dc.contributor.authorNutt, D.J.
dc.contributor.authorPersico, A.
dc.contributor.authorPerugi, G.
dc.contributor.authorPessiglione, M.
dc.contributor.authorPreuss, U.W.
dc.contributor.authorRoiser, J.P.
dc.contributor.authorRossini, P.M.
dc.contributor.authorRybakowski, J.K.
dc.contributor.authorSandi, C.
dc.contributor.authorStephan, K.E.
dc.contributor.authorUndurraga, J.
dc.contributor.authorVieta, E.
dc.contributor.authorvan der Wee, N.
dc.contributor.authorWykes, T.
dc.contributor.authorHaro, J.M.
dc.contributor.authorWittchen, H.U.
dc.date.accessioned2014-05-14T11:31:01Z
dc.date.available2014-05-14T11:31:01Z
dc.date.issued2014-01-01
dc.identifier.citationSchumann , G , Binder , E B , Holte , A , de Kloet , E R , Oedegaard , K J , Robbins , T W , Walker-Tilley , T R , Bitter , I , Brown , V J , Buitelaar , J , Ciccocioppo , R , Cools , R , Escera , C , Fleischhacker , W , Flor , H , Frith , C D , Heinz , A , Johnsen , E , Kirschbaum , C , Klingberg , T , Lesch , K-P , Lewis , S , Maier , W , Mann , K , Martinot , J-L , Meyer-Lindenberg , A , Müller , C P , Müller , W E , Nutt , D J , Persico , A , Perugi , G , Pessiglione , M , Preuss , U W , Roiser , J P , Rossini , P M , Rybakowski , J K , Sandi , C , Stephan , K E , Undurraga , J , Vieta , E , van der Wee , N , Wykes , T , Haro , J M & Wittchen , H U 2014 , ' Stratified medicine for mental disorders ' European Neuropsychopharmacology , vol. 24 , no. 1 , pp. 5-50 . https://doi.org/10.1016/j.euroneuro.2013.09.010en
dc.identifier.issn0924-977X
dc.identifier.otherPURE: 118404181
dc.identifier.otherPURE UUID: 6c7599d9-c12b-4397-99cf-edd1f7ba11db
dc.identifier.otherScopus: 84892623734
dc.identifier.urihttp://www.scopus.com/inward/record.url?eid=2-s2.0-84892623734&partnerID=8YFLogxKen
dc.descriptionFunding for this study was provided by the European Commission's Seventh Framework Programme Project ROAMER– A Roadmap for Mental Health Research in Europe (FP7-HEALTH-2011/No.282586.en
dc.description.abstractThere is recognition that biomedical research into the causes of mental disorders and their treatment needs to adopt new approaches to research. Novel biomedical techniques have advanced our understanding of how the brain develops and is shaped by behaviour and environment. This has led to the advent of stratified medicine, which translates advances in basic research by targeting aetiological mechanisms underlying mental disorder. The resulting increase in diagnostic precision and targeted treatments may provide a window of opportunity to address the large public health burden, and individual suffering associated with mental disorders.While mental health and mental disorders have significant representation in the "health, demographic change and wellbeing" challenge identified in Horizon 2020, the framework programme for research and innovation of the European Commission (2014-2020), and in national funding agencies, clear advice on a potential strategy for mental health research investment is needed. The development of such a strategy is supported by the EC-funded "Roadmap for Mental Health Research" (ROAMER) which will provide recommendations for a European mental health research strategy integrating the areas of biomedicine, psychology, public health well being, research integration and structuring, and stakeholder participation. Leading experts on biomedical research on mental disorders have provided an assessment of the state of the art in core psychopathological domains, including arousal and stress regulation, affect, cognition social processes, comorbidity and pharmacotherapy. They have identified major advances and promising methods and pointed out gaps to be addressed in order to achieve the promise of a stratified medicine for mental disorders.
dc.format.extent46
dc.language.isoeng
dc.relation.ispartofEuropean Neuropsychopharmacologyen
dc.rights© 2013 Elsevier B.V. and ECNP. All rights reserved. Published as open access.en
dc.subjectMental disorderen
dc.subjectRoadmapen
dc.subjectStratified medicineen
dc.subjectPsychpathologyen
dc.subjectNeural processesen
dc.subjectTreatmenten
dc.subjectRM Therapeutics. Pharmacologyen
dc.subject.lccRMen
dc.titleStratified medicine for mental disordersen
dc.typeJournal articleen
dc.description.versionPublisher PDFen
dc.contributor.institutionUniversity of St Andrews.School of Psychology and Neuroscienceen
dc.contributor.institutionUniversity of St Andrews.Office of the Principalen
dc.contributor.institutionUniversity of St Andrews.Institute of Behavioural and Neural Sciencesen
dc.identifier.doihttps://doi.org/10.1016/j.euroneuro.2013.09.010
dc.description.statusPeer revieweden


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