Ovarian volume correlates strongly with the number of non-growing follicles in the human ovary
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A reliable indirect measure of ovarian reserve for the individual woman remains a challenge for reproductive specialists. Using descriptive statistics from a large-scale study of ovarian volumes, we have developed a normative model for healthy females for ages 25 through 85. For average values, this model has a strong and positive correlation (r=0.89) with our recent model of nongrowing follicles (NGFs) in the human ovary for ages 25 through 51. When both models are log-adjusted, the correlation increases to r=0.99, over the full range of ovarian volume. Furthermore we can deduce that an ovary of 3 cm3 volume (or less) contains approximately 1000 NGF (or fewer). These strong correlations indicate that ovarian volume is a useful factor in the indirect estimation of human ovarian reserve for the individual woman.
Kelsey , T & Wallace , W H B 2012 , ' Ovarian volume correlates strongly with the number of non-growing follicles in the human ovary ' Obstetrics and Gynecology International , vol. 2012 , 305025 . DOI: 10.1155/2012/305025
Obstetrics and Gynecology International
Copyright © 2012 Thomas W. Kelsey and W. Hamish B. Wallace. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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