Tissue surface as the reference arm in Fourier domain optical coherence tomography
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We present a simple method applicable to common-path Fourier domain optical coherence tomography (OCT) in which the tissue surface is used as the reference arm. We propose using aluminium hydroxide powder as a potential tissue surface diffuser to allow wider application of this method. This technique allows one to avoid placing a reference arm reflective element, such as glass plate, on tissue, and intrinsically avoids both coherent and complex conjugate mirror artifacts associated with glass plates. Aluminium hydroxide can be sprayed onto tissue using spray nozzles commonly found in endoscopes. The sensitivity of the tissue reference arm common-path OCT image is 94 dB for a 50-mu s charge-coupled device integration time, and 97.5 dB for a 200-mu s CCD integration time. (C) 2012 Society of Photo-Optical Instrumentation Engineers (SPIE). [DOL 10.1117/1.JBO.17.7.071305]
Krstajic , N , Brown , C T A , Dholakia , K & Giardini , M E 2012 , ' Tissue surface as the reference arm in Fourier domain optical coherence tomography ' Journal of Biomedical Optics , vol 17 , no. 7 , 071305 . DOI: 10.1117/1.JBO.17.7.071305
Journal of Biomedical Optics
Nikola Krstajic, Christian T.A. Brown, Kishan Dholakia and Mario E. Giardini, "Tissue surface as the reference arm in Fourier domain optical coherence tomography",J. Biomed. Opt. 17, 071305 (2012). Copyright 2012 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic electronic or print reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited. http://dx.doi.org/10.1117/1.JBO.17.7.071305
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