Mechanisms of gene duplication and translocation and progress towards understanding their relative contributions to animal genome evolution
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Duplication of genetic material is clearly a major route to genetic change, with consequences for both evolution and disease. A variety of forms and mechanisms of duplication are recognised, operating across the scales of a few base pairs upto entire genomes. With the ever-increasing amounts of gene and genome sequence data that are becoming available, our understanding of the extent of duplication is greatly improving, both in terms of the scales of duplication events as well as their rates of occurrence. An accurate understanding of these processes is vital if we are to properly understand important events in evolution as well as mechanisms operating at the level of genome organisation. Here we will focus on duplication in animal genomes and how the duplicated sequences are distributed, with the aim of maintaining a focus on principles of evolution and organisation that are most directly applicable to the shaping of our own genome.
Mendivil Ramos , O & Ferrier , D E K 2012 , ' Mechanisms of gene duplication and translocation and progress towards understanding their relative contributions to animal genome evolution ' International Journal of Evolutionary Biology , vol. 2012 , 846421 . DOI: 10.1155/2012/846421
International Journal of Evolutionary Biology
Copyright © 2012 Olivia Mendivil Ramos and David E. K. Ferrier. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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