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Neuroscience-informed classification of prevention interventions in substance use disorders : an RDoC-based approach
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dc.contributor.author | Rezapour, Tara | |
dc.contributor.author | Rafei, Parnian | |
dc.contributor.author | Baldacchino, Alex | |
dc.contributor.author | Conrod, Patricia J. | |
dc.contributor.author | Dom, Geert | |
dc.contributor.author | Fishbein, Diana H. | |
dc.contributor.author | Kazemi, Atefeh | |
dc.contributor.author | Hendriks, Vincent | |
dc.contributor.author | Newton, Nicola | |
dc.contributor.author | Riggs, Nathaniel R. | |
dc.contributor.author | Squeglia, Lindsay M. | |
dc.contributor.author | Teesson, Maree | |
dc.contributor.author | Vassileva, Jasmin | |
dc.contributor.author | Verdejo-Garcia, Antonio | |
dc.contributor.author | Ekhtiari, Hamed | |
dc.date.accessioned | 2024-03-11T16:30:13Z | |
dc.date.available | 2024-03-11T16:30:13Z | |
dc.date.issued | 2024-04 | |
dc.identifier | 299324529 | |
dc.identifier | 3324a91e-ccac-439f-810f-b40a6fb36ebf | |
dc.identifier | 85187210346 | |
dc.identifier.citation | Rezapour , T , Rafei , P , Baldacchino , A , Conrod , P J , Dom , G , Fishbein , D H , Kazemi , A , Hendriks , V , Newton , N , Riggs , N R , Squeglia , L M , Teesson , M , Vassileva , J , Verdejo-Garcia , A & Ekhtiari , H 2024 , ' Neuroscience-informed classification of prevention interventions in substance use disorders : an RDoC-based approach ' , Neuroscience and Biobehavioral Reviews , vol. 159 , 105578 . https://doi.org/10.1016/j.neubiorev.2024.105578 | en |
dc.identifier.issn | 0149-7634 | |
dc.identifier.other | Jisc: 1760690 | |
dc.identifier.other | ORCID: /0000-0002-5388-7376/work/154531944 | |
dc.identifier.uri | https://hdl.handle.net/10023/29468 | |
dc.description.abstract | Neuroscience has contributed to uncover the mechanisms underpinning substance use disorders (SUD). The next frontier is to leverage these mechanisms as active targets to create more effective interventions for SUD treatment and prevention. Recent large-scale cohort studies from early childhood are generating multiple levels of neuroscience-based information with the potential to inform the development and refinement of future preventive strategies. However, there are still no available well-recognized frameworks to guide the integration of these multi-level datasets into prevention interventions. The Research Domain Criteria (RDoC) provides a neuroscience-based multi-system framework that is well suited to facilitate translation of neurobiological mechanisms into behavioral domains amenable to preventative interventions. We propose a novel RDoC-based framework for prevention science and adapted the framework for the existing preventive interventions. From a systematic review of randomized controlled trials using a person-centered drug/alcohol preventive approach for adolescents, we identified 22 unique preventive interventions. By teasing apart these 22 interventions into the RDoC domains, we proposed distinct neurocognitive trajectories which have been recognized as precursors or risk factors for SUDs, to be targeted, engaged and modified for effective addiction prevention. | |
dc.format.extent | 14 | |
dc.format.extent | 1246712 | |
dc.language.iso | eng | |
dc.relation.ispartof | Neuroscience and Biobehavioral Reviews | en |
dc.subject | Adolescence | en |
dc.subject | Interventions | en |
dc.subject | Substance use disorders | en |
dc.subject | Research Domain Criteria | en |
dc.subject | Prevention | en |
dc.subject | Neuroscience | en |
dc.subject | RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry | en |
dc.subject | 3rd-NDAS | en |
dc.subject | AC | en |
dc.subject.lcc | RC0321 | en |
dc.title | Neuroscience-informed classification of prevention interventions in substance use disorders : an RDoC-based approach | en |
dc.type | Journal article | en |
dc.contributor.institution | University of St Andrews. Population and Behavioural Science Division | en |
dc.contributor.institution | University of St Andrews. Centre for Minorities Research (CMR) | en |
dc.contributor.institution | University of St Andrews. School of Medicine | en |
dc.identifier.doi | 10.1016/j.neubiorev.2024.105578 | |
dc.description.status | Peer reviewed | en |
dc.date.embargoedUntil | 2024-03-08 |
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