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The 10-year follow-up of a community-based cohort of people with diabetes : the incidence of foot ulceration and death
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dc.contributor.author | Shijat, Mohammed | |
dc.contributor.author | Crawford, Fay | |
dc.contributor.author | Cezard, Genevieve Isabelle | |
dc.contributor.author | Papathomas, Michail | |
dc.date.accessioned | 2023-11-23T15:30:01Z | |
dc.date.available | 2023-11-23T15:30:01Z | |
dc.date.issued | 2023-11-21 | |
dc.identifier | 294268468 | |
dc.identifier | f81f84df-d6b5-4474-9dc4-fa2359afed1f | |
dc.identifier | 85177598885 | |
dc.identifier.citation | Shijat , M , Crawford , F , Cezard , G I & Papathomas , M 2023 , ' The 10-year follow-up of a community-based cohort of people with diabetes : the incidence of foot ulceration and death ' , Endocrinology, Diabetes & Metabolism , vol. Early View , e459 . https://doi.org/10.1002/edm2.459 | en |
dc.identifier.issn | 2398-9238 | |
dc.identifier.other | ORCID: /0000-0002-5897-695X/work/147473256 | |
dc.identifier.uri | https://hdl.handle.net/10023/28756 | |
dc.description | Funding: This work was funded as part of a wider project by the National Institute for Health Research (NIHR) Health Technology Assessment (HTA) Programme (HTA project: 15/171/01). | en |
dc.description.abstract | Background: Identifying people with diabetes who are likely to experience a foot ulcer is an important part of preventative care. Many cohort studies report predictive models for foot ulcerations and for people with diabetes, but reports of long-term outcomes are scarce. Aim: We aimed to develop a predictive model for foot ulceration in diabetes using a range of potential risk factors with a follow-up of 10 years after recruitment. A new foot ulceration was the outcome of interest and death was the secondary outcome of interest. Design: A 10-year follow-up cohort study. Methods: 1193 people with a diagnosis of diabetes who took part in a study in 2006–2007 were invited to participate in a 10-year follow-up. We developed a prognostic model for the incidence of incident foot ulcerations using a survival analysis, Cox proportional hazards model. We also utilised survival analysis Kaplan–Meier curves, and relevant tests, to assess the association between the predictor variables for foot ulceration and death. Results: At 10-year follow-up, 41% of the original study population had died and more than 18% had developed a foot ulcer. The predictive factors for foot ulceration were an inability to feel a 10 g monofilament or vibration from a tuning fork, previous foot ulceration and duration of diabetes. Conclusions: The prognostic model shows an increased risk of ulceration for those with previous history of foot ulcerations, insensitivity to a 10 g monofilament, a tuning fork and duration of diabetes. The incidence of foot ulceration at 10-year follow-up was 18%; however, the risk of death for this community-based population was far greater than the risk of foot ulceration. | |
dc.format.extent | 13 | |
dc.format.extent | 1973767 | |
dc.language.iso | eng | |
dc.relation.ispartof | Endocrinology, Diabetes & Metabolism | en |
dc.subject | Cohort study | en |
dc.subject | Diabetes mellitus | en |
dc.subject | Foot ulcer | en |
dc.subject | Prediction | en |
dc.subject | RA0421 Public health. Hygiene. Preventive Medicine | en |
dc.subject | RR-NDAS | en |
dc.subject | SDG 3 - Good Health and Well-being | en |
dc.subject.lcc | RA0421 | en |
dc.title | The 10-year follow-up of a community-based cohort of people with diabetes : the incidence of foot ulceration and death | en |
dc.type | Journal article | en |
dc.contributor.institution | University of St Andrews. Statistics | en |
dc.contributor.institution | University of St Andrews. Centre for Research into Ecological & Environmental Modelling | en |
dc.identifier.doi | 10.1002/edm2.459 | |
dc.description.status | Peer reviewed | en |
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