Efficient biotransformations in Cunninghamella elegans and Streptomyces sp. JCM9888 of selectively fluorinated benzoic acids to the corresponding benzamides and benzyl alcohols
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An efficient conversion of ortho, meta and para fluoro- and trifluoromethyl-substituted benzoic acids to the corresponding benzamides in fermentations of the soil bacterium Streptomyces sp. JCM9888 is described. We also report the efficient reduction of the same class of substrates to the corresponding benzyl alcohols with the fungi Cunninghamella elegans. These biotransformations were surprisingly efficient and may have value as disruptive technologies in process chemistry.
Oke , O O , Chen , Y , Isanbor , C , Asekun , O T & O'Hagan , D 2023 , ' Efficient biotransformations in Cunninghamella elegans and Streptomyces sp . JCM9888 of selectively fluorinated benzoic acids to the corresponding benzamides and benzyl alcohols ' , Biocatalysis and Biotransformation , vol. Latest Articles . https://doi.org/10.1080/10242422.2023.2267156
Biocatalysis and Biotransformation
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DescriptionSupport was received from the Commonwealth Scholarship Council for a Split Site Studentship (OO) and also from the Royal Society of Chemistry for a travel Grant (C.I).
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