Efficient biotransformations in Cunninghamella elegans and Streptomyces sp. JCM9888 of selectively fluorinated benzoic acids to the corresponding benzamides and benzyl alcohols
Abstract
An efficient conversion of ortho, meta and para fluoro- and trifluoromethyl-substituted benzoic acids to the corresponding benzamides in fermentations of the soil bacterium Streptomyces sp. JCM9888 is described. We also report the efficient reduction of the same class of substrates to the corresponding benzyl alcohols with the fungi Cunninghamella elegans. These biotransformations were surprisingly efficient and may have value as disruptive technologies in process chemistry.
Citation
Oke , O O , Chen , Y , Isanbor , C , Asekun , O T & O'Hagan , D 2023 , ' Efficient biotransformations in Cunninghamella elegans and Streptomyces sp . JCM9888 of selectively fluorinated benzoic acids to the corresponding benzamides and benzyl alcohols ' , Biocatalysis and Biotransformation , vol. Latest Articles . https://doi.org/10.1080/10242422.2023.2267156
Publication
Biocatalysis and Biotransformation
Status
Peer reviewed
ISSN
1024-2422Type
Journal article
Description
Support was received from the Commonwealth Scholarship Council for a Split Site Studentship (OO) and also from the Royal Society of Chemistry for a travel Grant (C.I).Collections
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