Heavy metal-associated isoprenylated plant proteins (HIPPs) at plasmodesmata : exploring the link between localization and function
Abstract
Heavy metal-associated isoprenylated plant proteins (HIPPs) are a metallochaperone-like protein family comprising a combination of structural features unique to vascular plants. HIPPs possess both one or two heavy metal-binding domains and an isoprenylation site, facilitating a posttranslational protein lipid modification. Recent work has characterized individual HIPPs across numerous different species and provided evidence for varied functionalities. Interestingly, a significant number of HIPPs have been identified in proteomes of plasmodesmata (PD)—nanochannels mediating symplastic connectivity within plant tissues that play pivotal roles in intercellular communication during plant development as well as responses to biotic and abiotic stress. As characterized functions of many HIPPs are linked to stress responses, plasmodesmal HIPP proteins are potentially interesting candidate components of signaling events at or for the regulation of PD. Here, we review what is known about PD-localized HIPP proteins specifically, and how the structure and function of HIPPs more generally could link to known properties and regulation of PD.
Citation
Barr , Z K , Werner , T & Tilsner , J 2023 , ' Heavy metal-associated isoprenylated plant proteins (HIPPs) at plasmodesmata : exploring the link between localization and function ' , Plants , vol. 12 , no. 16 , 3015 . https://doi.org/10.3390/plants12163015
Publication
Plants
Status
Peer reviewed
ISSN
2223-7747Type
Journal item
Description
Funding: This work was supported by the U.K. Biotechnology and Biological Sciences Research Council (BBSRC) through an Eastbio Doctoral Training Partnership scholarship to Z.B, and by the Austrian Science Fund grant P 30945 to T.W. Work in the J.T. laboratory is supported by the Scottish Government’s Rural and Environment Science and Analytical Services Division (RESAS).Collections
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