Files in this item
Caveat medicus : it's time to re-think stratification, you may not be helping
Item metadata
dc.contributor.author | Arandelovic, Oggie | |
dc.date.accessioned | 2023-05-15T15:30:22Z | |
dc.date.available | 2023-05-15T15:30:22Z | |
dc.date.issued | 2023-12-01 | |
dc.identifier | 285800526 | |
dc.identifier | c59b33aa-589d-4ea6-819b-c53c66d72612 | |
dc.identifier | 85160406511 | |
dc.identifier.citation | Arandelovic , O 2023 , ' Caveat medicus : it's time to re-think stratification, you may not be helping ' , Biomarkers Insights , vol. 18 . https://doi.org/10.1177/11772719231174746 | en |
dc.identifier.issn | 1177-2719 | |
dc.identifier.uri | https://hdl.handle.net/10023/27622 | |
dc.description.abstract | Background The focus of the present Letter is on the large and seemingly fertile body of work captured under the umbrella of ‘patient stratification’. Objectives I identify and explain a fundamental methodological flaw underlying the manner in which the development of an increasingly large number of new stratification strategies is approached. Design I show an inherent conflict between the assumptions made, and the very purpose of stratification and its application in practice. Methods I analyse the methodological underpinnings of stratification as presently done and draw parallels with conceptually similarly flawed precedents which are now widely recognized. Results The highlighted flaw is shown to undermine the overarching ultimate goal of improved patient outcomes by undue fixation on an ill-founded proxy. Conclusion I issue a call for a re-think of the problem and the processes leading to the adoption of new stratification strategies in the clinic. | |
dc.format.extent | 3 | |
dc.format.extent | 230744 | |
dc.language.iso | eng | |
dc.relation.ispartof | Biomarkers Insights | en |
dc.subject | Risk | en |
dc.subject | Biomarkers | en |
dc.subject | Personalized | en |
dc.subject | Targeted | en |
dc.subject | Precision | en |
dc.subject | 3rd-DAS | en |
dc.subject | MCC | en |
dc.title | Caveat medicus : it's time to re-think stratification, you may not be helping | en |
dc.type | Journal article | en |
dc.contributor.institution | University of St Andrews. School of Computer Science | en |
dc.identifier.doi | https://doi.org/10.1177/11772719231174746 | |
dc.description.status | Peer reviewed | en |
This item appears in the following Collection(s)
Items in the St Andrews Research Repository are protected by copyright, with all rights reserved, unless otherwise indicated.