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Synthesis and spectroscopic and structural characterization of three new 2-methyl-4-styrylquinolines formed using Friedlander reactions between (2-aminophenyl)chalcones and acetone
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dc.contributor.author | Rocío Vera, Diana | |
dc.contributor.author | Mantilla, Juan P. | |
dc.contributor.author | Palma, Alirio | |
dc.contributor.author | Cobo, Justo | |
dc.contributor.author | Glidewell, Christopher | |
dc.date.accessioned | 2022-10-05T12:30:04Z | |
dc.date.available | 2022-10-05T12:30:04Z | |
dc.date.issued | 2022-10-05 | |
dc.identifier | 281144047 | |
dc.identifier | ce542a15-cdcd-4225-b6b9-9b6788f46303 | |
dc.identifier | 000865947300003 | |
dc.identifier | 85139572090 | |
dc.identifier.citation | Rocío Vera , D , Mantilla , J P , Palma , A , Cobo , J & Glidewell , C 2022 , ' Synthesis and spectroscopic and structural characterization of three new 2-methyl-4-styrylquinolines formed using Friedlander reactions between (2-aminophenyl)chalcones and acetone ' , Acta Crystallographica Section C Structural Chemistry , vol. 78 , no. 10 , pp. 524-530 . https://doi.org/10.1107/S2053229622008634 | en |
dc.identifier.issn | 2053-2296 | |
dc.identifier.uri | https://hdl.handle.net/10023/26135 | |
dc.description | Funding for this research was provided by: Vicerrectoría de Investigación y Extensión of the Industrial University of Santander (grant No. 2680 to AP); Universidad de Jaén and the Consejería de Economía, Innovación, Ciencia y Empleo (Junta de Andalucá, Spain) (award to JC). | en |
dc.description.abstract | Three new 2-methyl-4-styrylquinoline derivatives have been synthesized in high yields using Friedländer reactions between chalcones [1-(2-aminophenyl)-3-arylprop-2-en-1-ones] and acetone, and characterized using IR, 1H and 13C NMR spectroscopy, and mass spectrometry, and by crystal structure analysis. In (E)-4-(4-fluorostyryl)-2-methylquinoline, C18H14FN, (I), the molecules are joined into cyclic centrosymmetric dimers by C—H⋯N hydrogen bonds and these dimers are linked into sheets by π–π stacking interactions. The molecules of (E)-2-methyl-4-[4-(trifluoromethyl)styryl]quinoline, C19H14F3N, (II), are linked into cyclic centrosymmetric dimers by C—H⋯π hydrogen bonds and these dimers are linked into chains by a single π–π stacking interaction. There are no significant hydrogen bonds in the structure of (E)-4-(2,6-dichlorostyryl)-2-methylquinoline, C18H13Cl2N, (III), but molecules related by translation along [010] form stacks with an intermolecular spacing of only 3.8628 (2) Å. Comparisons are made with the structures of some related compounds. | |
dc.format.extent | 1144340 | |
dc.language.iso | eng | |
dc.relation.ispartof | Acta Crystallographica Section C Structural Chemistry | en |
dc.subject | Synthesis | en |
dc.subject | Quinoline | en |
dc.subject | Friedlander reaction | en |
dc.subject | NMR spectroscopy | en |
dc.subject | Crystal structure | en |
dc.subject | Molecular conformation | en |
dc.subject | Hydrogen bonding | en |
dc.subject | Supramolecular assembly | en |
dc.subject | QD Chemistry | en |
dc.subject | DAS | en |
dc.subject.lcc | QD | en |
dc.title | Synthesis and spectroscopic and structural characterization of three new 2-methyl-4-styrylquinolines formed using Friedlander reactions between (2-aminophenyl)chalcones and acetone | en |
dc.type | Journal article | en |
dc.contributor.institution | University of St Andrews. School of Chemistry | en |
dc.identifier.doi | 10.1107/S2053229622008634 | |
dc.description.status | Peer reviewed | en |
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