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dc.contributor.authorCanny, Anne
dc.contributor.authorMason, Bruce
dc.contributor.authorStephen, Jacqueline
dc.contributor.authorHopkins, Samantha
dc.contributor.authorWall, Lucy
dc.contributor.authorChristie, Alan
dc.contributor.authorSkipworth, Richard Je
dc.contributor.authorBowden, Joanna
dc.contributor.authorGraham, Louise
dc.contributor.authorKendall, Marilyn
dc.contributor.authorWeir, Christopher J
dc.contributor.authorBoyd, Kirsty
dc.identifier.citationCanny , A , Mason , B , Stephen , J , Hopkins , S , Wall , L , Christie , A , Skipworth , R J , Bowden , J , Graham , L , Kendall , M , Weir , C J & Boyd , K 2022 , ' Advance care planning in primary care for patients with gastrointestinal cancer : feasibility randomised trial ' , British Journal of General Practice , vol. 72 , no. 721 , pp. e571-e580 .
dc.identifier.otherPURE: 280797055
dc.identifier.otherPURE UUID: 3d818e2b-0a28-4806-ad63-12a452b3dee3
dc.identifier.otherJisc: 486868
dc.identifier.otherpmcid: PMC9242676
dc.identifier.otherpmid: 35760566
dc.identifier.otherScopus: 85135378346
dc.identifier.otherWOS: 000821900000001
dc.descriptionFunding: This study was funded by Macmillan Cancer Support (reference: 6488086). Christopher J Weir was also supported in this work by NHS Lothian via Edinburgh Clinical Trials Unit ( Identifier: NCT03719716).en
dc.description.abstractBackground Advance (anticipatory) care planning (ACP) requires discussions between patients and healthcare professionals about planning for future deterioration in health. ACP improves care coordination but uptake is limited and often deferred. Aim To assess the feasibility and acceptability to patients, carers, and GPs of a primary care ACP intervention for people with incurable oesophageal, gastric, or pancreatic cancer. Design and setting A 12-month feasibility randomised controlled trial (RCT) in a Scottish Cancer Network. Method Patients aged ≥18 years starting palliative oncology treatment were randomised 1:1 to an ACP intervention or standard care. Patients in the intervention group received an oncologist letter supporting them to request a GP review along with a patient information leaflet about ACP. Pre-specified analyses with masking included trial recruitment and retention, ACP completion, and quality-of-life questionnaires (EuroQol EQ-5D-5L and ICECAP Supportive Care Measure) at baseline, 6, 12, 24, and 48 weeks. Qualitative interviews with purposive sampling explored patient, carer, and GP experiences. Results Of 99 eligible participants (269 screened), 46% were recruited (n = 46) and randomised; 25 to intervention and 21 to control. By 12 weeks, 45% (n = 9/20) of the individuals in the intervention and 59% (n = 10/17) in the control group had a documented ACP plan. By 24 weeks, 30% (n = 14) had died; in the remaining participants quality of life was maintained at 24 weeks except for physical symptoms. Social norms associating ACP with dying were prevalent among 23 participants interviewed. No psychological or clinical harms were identified. Conclusion An RCT of ACP for people with incurable cancer in primary care is feasible. Patient, carer, and GP attitudes and behaviours determined acceptability and timing of care planning.
dc.relation.ispartofBritish Journal of General Practiceen
dc.rightsCopyright © 2022 The Authors. This article is Open Access: CC BY 4.0 licence (
dc.subjectPrimary health careen
dc.subjectGeneral practiceen
dc.subjectMixed methodsen
dc.subjectAdvance care planningen
dc.subjectAnticipatory care planningen
dc.subjectRC0254 Neoplasms. Tumors. Oncology (including Cancer)en
dc.subjectRA Public aspects of medicineen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.titleAdvance care planning in primary care for patients with gastrointestinal cancer : feasibility randomised trialen
dc.typeJournal articleen
dc.description.versionPublisher PDFen
dc.contributor.institutionUniversity of St Andrews. Arctic Research Centreen
dc.contributor.institutionUniversity of St Andrews. School of Medicineen
dc.description.statusPeer revieweden

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