On the trail of iron uptake in ancestral Cyanobacteria on early Earth
MetadataShow full item record
Altmetrics Handle Statistics
Altmetrics DOI Statistics
Cyanobacteria oxygenated Earth's atmosphere ~2.4 billion years ago, during the Great Oxygenation Event (GOE), through oxygenic photosynthesis. Their high iron requirement was presumably met by high levels of Fe(II) in the anoxic Archean environment. We found that many deeply branching Cyanobacteria, including two Gloeobacter and four Pseudanabaena spp., cannot synthesize the Fe(II) specific transporter, FeoB. Phylogenetic and relaxed molecular clock analyses find evidence that FeoB and the Fe(III) transporters, cFTR1 and FutB, were present in Proterozoic, but not earlier Archaean lineages of Cyanobacteria. Furthermore Pseudanabaena sp. PCC7367, an early diverging marine, benthic strain grown under simulated Archean conditions, constitutively expressed cftr1, even after the addition of Fe(II). Our genetic profiling suggests that, prior to the GOE, ancestral Cyanobacteria may have utilized alternative metal iron transporters such as ZIP, NRAMP, or FicI, and possibly also scavenged exogenous siderophore bound Fe(III), as they only acquired the necessary Fe(II) and Fe(III) transporters during the Proterozoic. Given that Cyanobacteria arose 3.3-3.6 billion years ago, it is possible that limitations in iron uptake may have contributed to the delay in their expansion during the Archean, and hence the oxygenation of the early Earth.
Enzingmüller-Bleyl , T C , Boden , J S , Herrmann , A J , Ebel , K W , Sánchez-Baracaldo , P , Frankenberg-Dinkel , N & Gehringer , M M 2022 , ' On the trail of iron uptake in ancestral Cyanobacteria on early Earth ' , Geobiology , vol. Early View . https://doi.org/10.1111/gbi.12515
Copyright © 2022 The Authors. Geobiology published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
DescriptionThis project was funded by the German Research Foundation SPP1833, DFG, Grant numbers: GE2558/3-1 & GE2558/4-1 awarded to MMG, a University of Bristol Graduate Teaching Scholarship awarded to J.S.B. and a Royal Society University Research Fellowship awarded to P.S-B. Open Access funding enabled and organized by Projekt DEAL.
Items in the St Andrews Research Repository are protected by copyright, with all rights reserved, unless otherwise indicated.