Files in this item
Prevalence of chronic pain in LTCs and multimorbidity : a cross-sectional study using UK Biobank
Item metadata
dc.contributor.author | McQueenie, Ross | |
dc.contributor.author | Jani, Bhautesh Dinesh | |
dc.contributor.author | Siebert, Stefan | |
dc.contributor.author | McLoone, Philip | |
dc.contributor.author | McCowan, Colin | |
dc.contributor.author | Macdonald, Sara | |
dc.contributor.author | Mair, Frances S | |
dc.contributor.author | Nicholl, Barbara I | |
dc.date.accessioned | 2022-01-06T17:30:05Z | |
dc.date.available | 2022-01-06T17:30:05Z | |
dc.date.issued | 2021-12-21 | |
dc.identifier | 274961038 | |
dc.identifier | ab15947d-d5d5-4620-8f90-db39ee1d2c32 | |
dc.identifier.citation | McQueenie , R , Jani , B D , Siebert , S , McLoone , P , McCowan , C , Macdonald , S , Mair , F S & Nicholl , B I 2021 , ' Prevalence of chronic pain in LTCs and multimorbidity : a cross-sectional study using UK Biobank ' , Journal of Multimorbidity and Comorbidity , vol. 11 . https://doi.org/10.1177/26335565211005870 | en |
dc.identifier.issn | 2633-5565 | |
dc.identifier.other | ORCID: /0000-0002-9466-833X/work/105957152 | |
dc.identifier.uri | https://hdl.handle.net/10023/24615 | |
dc.description | This study was funded by Versus Arthritis (grant number 21970). This research has been conducted using the UK Biobank Resource, approved project number 14151. | en |
dc.description.abstract | Objectives : Chronic pain is often experienced alongside other long-term conditions (LTCs), yet our understanding of this, particularly in relation to multimorbidity (≥2 LTCs) is poor. We aimed to examine associations between the presence/extent of chronic pain with type/number of LTCs experienced. Methods : We examined the relationship between number/type of LTCs (N = 45) in UK Biobank participants (n = 500,295) who self-reported chronic pain lasting ≥3 months in seven body sites or widespread. Relative risk ratios (RRR) for presence/extent of chronic pain sites were compared using logistic regression adjusted for sociodemographic (sex/age/socioeconomic status) and lifestyle factors (smoking/alcohol intake/BMI/physical activity). Results : 218,648 participants self-reported chronic pain. Of these, 69.1% reported ≥1 LTC and 36.2% reported ≥2 LTCs. In 31/45 LTCs examined, >50% of participants experienced chronic pain. Chronic pain was common with migraine/headache and irritable bowel syndrome where pain is a primary symptom, but also with mental health conditions and diseases of the digestive system. Participants with >4 LTCs were over three times as likely to have chronic pain (RRR 3.56, 95% confidence intervals (CIs) 3.44–3.68) and 20 times as likely to have widespread chronic pain (RRR 20.13, 95% CI 18.26–22.19) as those with no LTCs. Conclusions: Chronic pain is extremely common across a wide range of LTCs. People with multimorbidity were at higher risk of having a greater extent of chronic pain. These results show that chronic pain is a key factor for consideration in the management of patients with LTCs or multimorbidity. | |
dc.format.extent | 10 | |
dc.format.extent | 465648 | |
dc.language.iso | eng | |
dc.relation.ispartof | Journal of Multimorbidity and Comorbidity | en |
dc.subject | Chronic pain | en |
dc.subject | Prevalence | en |
dc.subject | Multimorbidity | en |
dc.subject | Long-term conditions | en |
dc.subject | QH426 Genetics | en |
dc.subject | R Medicine | en |
dc.subject | 3rd-DAS | en |
dc.subject | SDG 3 - Good Health and Well-being | en |
dc.subject.lcc | QH426 | en |
dc.subject.lcc | R | en |
dc.title | Prevalence of chronic pain in LTCs and multimorbidity : a cross-sectional study using UK Biobank | en |
dc.type | Journal article | en |
dc.contributor.institution | University of St Andrews. School of Medicine | en |
dc.contributor.institution | University of St Andrews. Sir James Mackenzie Institute for Early Diagnosis | en |
dc.contributor.institution | University of St Andrews. Population and Behavioural Science Division | en |
dc.identifier.doi | 10.1177/26335565211005870 | |
dc.description.status | Peer reviewed | en |
dc.identifier.url | http://eprints.gla.ac.uk/236453/ | en |
This item appears in the following Collection(s)
Items in the St Andrews Research Repository are protected by copyright, with all rights reserved, unless otherwise indicated.