Metal-ligand cooperation facilitates bond activation and catalytic hydrogenation with zinc pincer complexes
Date
26/08/2020Metadata
Show full item recordAbstract
A series of PNP zinc pincer complexes capable of bond activation via aromatization/dearomatization metal-ligand cooperation (MLC) were prepared and characterized. Reversible heterolytic N-H and H-H bond activation by MLC is shown, in which hemilability of the phosphorus linkers plays a key role. Utilizing this zinc pincer system, base-free catalytic hydrogenation of imines and ketones under relatively mild conditions is demonstrated. A detailed mechanistic study supported by computation implicates the key role of MLC in facili-tating effective catalysis. This approach offers a new strategy for (de)hydrogenation and other catalytic transformations mediated by zinc and other main group metals.
Citation
Rauch , M , Kar , S , Kumar , A , Avram , L , Shimon , L J W & Milstein , D 2020 , ' Metal-ligand cooperation facilitates bond activation and catalytic hydrogenation with zinc pincer complexes ' , Journal of the American Chemical Society , vol. 142 , no. 34 , pp. 14513-14521 . https://doi.org/10.1021/jacs.0c05500
Publication
Journal of the American Chemical Society
Status
Peer reviewed
ISSN
0002-7863Type
Journal article
Description
We thank the European Research Council (ERC AdG 692775) for support of this research. M.R. acknowledges the Zuckerman STEM Leadership Program for a research fellowship. S.K. acknowledges the Sustainability and Energy Research Initiative (SAERI) Weizmann Institute of Science for a research fellowship. A. K. is thankful to the Feinberg Graduate School for the Senior Postdoctoral Fellowship.Collections
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