Synthetic studies on some fatty acids
Abstract
Part 1 – Synthesis of some Monoethenoid Acids with Potential Essential Fatty Acid Activity.
The cis-isomers of the four acids, teradec-8-enoic, hexadeco-10-enoic, octadic-12-enoic and cicos-14-enoic have been synthesised via the corresponding acetylenic acids.
Part II – Configuration of Natural 9-hydroxyoctadecanoic Acid.
9D-Hydroxyoctadecanoic acid has been synthesised and found to possess no measurable optical activity. It is suggested, on the evidence of a mixed melting point, that the natural acid has the d-configuration.
Part III – Synthetic studies on 6,8-Dihydroxyoctanoic Acid.
Two synthetic routes to 6,8-dihydroxyoctanoic acid have been examined. Both were eventually abandoned.
Type
Thesis, PhD Doctor of Philosopy
Collections
Items in the St Andrews Research Repository are protected by copyright, with all rights reserved, unless otherwise indicated.