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dc.contributor.authorEadie, Ewan
dc.contributor.authorBarnard, Isla M.R.
dc.contributor.authorIbbotson, Sally H.
dc.contributor.authorWood, Kenneth
dc.date.accessioned2021-02-22T09:30:11Z
dc.date.available2021-02-22T09:30:11Z
dc.date.issued2021-02-03
dc.identifier272465816
dc.identifier7691add7-e031-4920-97e5-a8af5320bbfa
dc.identifier85100354686
dc.identifier000614190200001
dc.identifier.citationEadie , E , Barnard , I M R , Ibbotson , S H & Wood , K 2021 , ' Extreme exposure to filtered far-UVC : a case study ' , Photochemistry and Photobiology , vol. Early view . https://doi.org/10.1111/php.13385en
dc.identifier.issn0031-8655
dc.identifier.otherRIS: urn:C3EBADE74FECE1B3F0D3A0D91DEB73CC
dc.identifier.urihttps://hdl.handle.net/10023/21468
dc.description.abstractFar-UVC devices are being commercially sold as "safe for humans" for the inactivation of SARS-CoV-2, without supporting human safety data. We felt there was a need for rapid proof-of-concept human self-exposure, to inform future controlled research and promote informed discussion. A Fitzpatrick Skin Type II individual exposed their inner forearms to large radiant exposures from a filtered Krypton-Chloride (KrCl) far-UVC system (SafeZoneUVC, Ushio Inc., Tokyo, Japan) with peak emission at 222 nm. No visible skin changes were observed at 1,500 mJcm-2, whereas skin yellowing that appeared immediately and resolved within 24 hours occurred with a 6,000 mJcm-2 exposure. No erythema was observed at any time point with exposures up to 18,000 mJcm-2. These results combined with Monte Carlo Radiative Transfer computer modelling suggest that filtering longer ultraviolet wavelengths is critical for the human skin safety of far-UVC devices. This work also contributes to growing arguments for the exploration of exposure limit expansion, which would subsequently enable faster inactivation of viruses.
dc.format.extent614761
dc.language.isoeng
dc.relation.ispartofPhotochemistry and Photobiologyen
dc.subjectRL Dermatologyen
dc.subject.lccRLen
dc.titleExtreme exposure to filtered far-UVC : a case studyen
dc.typeJournal itemen
dc.contributor.institutionUniversity of St Andrews. School of Physics and Astronomyen
dc.contributor.institutionUniversity of St Andrews. Centre for Biophotonicsen
dc.identifier.doihttps://doi.org/10.1111/php.13385
dc.description.statusPeer revieweden


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