Isolation of 5′-O-sulfamyladenosine and related 3′-O-β-glucosylated adenosines from the nucleocidin producer Streptomyces calvus
MetadataShow full item record
The isolation of three adenosine based metabolites 6–8 from Streptomyces calvus is reported. The metabolites are structurally related to the fluorine containing antibiotic nucleocidin 1 and two recently identified glycosylated fluoroadenosines 2 and 3, however in this case the three metabolites do not contain a fluorine, suggesting that the biosynthetic enzymes to the fluorometabolites also process their non-fluorinated counterparts.
Feng , X , Bello , D & O'Hagan , D 2021 , ' Isolation of 5′- O -sulfamyladenosine and related 3′- O -β-glucosylated adenosines from the nucleocidin producer Streptomyces calvus ' , RSC Advances , vol. 11 , no. 10 , pp. 5291-5294 . https://doi.org/10.1039/D1RA00235J
Copyright © 2021 The Author(s). Open Access article. This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.
DescriptionFunding: We thank EPSRC (EP/R013799/1) for a grant (DB) and the University of St Andrews for a Studentship (XF).
Items in the St Andrews Research Repository are protected by copyright, with all rights reserved, unless otherwise indicated.