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Genomic analysis of European Drosophila melanogaster populations reveals longitudinal structure, continent-wide selection, and previously unknown DNA viruses
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dc.contributor.author | Kapun, Martin | |
dc.contributor.author | Barrón, Maite G. | |
dc.contributor.author | Staubach, Fabian | |
dc.contributor.author | Obbard, Darren J. | |
dc.contributor.author | Wiberg, R. Axel W. | |
dc.contributor.author | Vieira, Jorge | |
dc.contributor.author | Goubert, Clément | |
dc.contributor.author | Rota-Stabelli, Omar | |
dc.contributor.author | Kankare, Maaria | |
dc.contributor.author | Bogaerts-Márquez, María | |
dc.contributor.author | Haudry, Annabelle | |
dc.contributor.author | Waidele, Lena | |
dc.contributor.author | Kozeretska, Iryna | |
dc.contributor.author | Pasyukova, Elena G. | |
dc.contributor.author | Loeschcke, Volker | |
dc.contributor.author | Pascual, Marta | |
dc.contributor.author | Vieira, Cristina P. | |
dc.contributor.author | Serga, Svitlana | |
dc.contributor.author | Montchamp-Moreau, Catherine | |
dc.contributor.author | Abbott, Jessica | |
dc.contributor.author | Gibert, Patricia | |
dc.contributor.author | Porcelli, Damiano | |
dc.contributor.author | Posnien, Nico | |
dc.contributor.author | Sánchez-Gracia, Alejandro | |
dc.contributor.author | Grath, Sonja | |
dc.contributor.author | Sucena, Élio | |
dc.contributor.author | Bergland, Alan O. | |
dc.contributor.author | Guerreiro, Maria Pilar Garcia | |
dc.contributor.author | Onder, Banu Sebnem | |
dc.contributor.author | Argyridou, Eliza | |
dc.contributor.author | Guio, Lain | |
dc.contributor.author | Schou, Mads Fristrup | |
dc.contributor.author | Deplancke, Bart | |
dc.contributor.author | Vieira, Cristina | |
dc.contributor.author | Ritchie, Michael G. | |
dc.contributor.author | Zwaan, Bas J. | |
dc.contributor.author | Tauber, Eran | |
dc.contributor.author | Orengo, Dorcas J. | |
dc.contributor.author | Puerma, Eva | |
dc.contributor.author | Aguadé, Montserrat | |
dc.contributor.author | Schmidt, Paul | |
dc.contributor.author | Parsch, John | |
dc.contributor.author | Betancourt, Andrea J. | |
dc.contributor.author | Flatt, Thomas | |
dc.contributor.author | González, Josefa | |
dc.date.accessioned | 2020-09-18T11:30:14Z | |
dc.date.available | 2020-09-18T11:30:14Z | |
dc.date.issued | 2020-09-01 | |
dc.identifier | 270228998 | |
dc.identifier | 465393ec-e471-44c6-ad02-9ad0b6a322dc | |
dc.identifier | 85090025034 | |
dc.identifier | 32413142 | |
dc.identifier | 000574386500016 | |
dc.identifier.citation | Kapun , M , Barrón , M G , Staubach , F , Obbard , D J , Wiberg , R A W , Vieira , J , Goubert , C , Rota-Stabelli , O , Kankare , M , Bogaerts-Márquez , M , Haudry , A , Waidele , L , Kozeretska , I , Pasyukova , E G , Loeschcke , V , Pascual , M , Vieira , C P , Serga , S , Montchamp-Moreau , C , Abbott , J , Gibert , P , Porcelli , D , Posnien , N , Sánchez-Gracia , A , Grath , S , Sucena , É , Bergland , A O , Guerreiro , M P G , Onder , B S , Argyridou , E , Guio , L , Schou , M F , Deplancke , B , Vieira , C , Ritchie , M G , Zwaan , B J , Tauber , E , Orengo , D J , Puerma , E , Aguadé , M , Schmidt , P , Parsch , J , Betancourt , A J , Flatt , T & González , J 2020 , ' Genomic analysis of European Drosophila melanogaster populations reveals longitudinal structure, continent-wide selection, and previously unknown DNA viruses ' , Molecular Biology and Evolution , vol. 37 , no. 9 , pp. 2661-2678 . https://doi.org/10.1093/molbev/msaa120 | en |
dc.identifier.issn | 0737-4038 | |
dc.identifier.other | ORCID: /0000-0001-7913-8675/work/80620093 | |
dc.identifier.uri | https://hdl.handle.net/10023/20643 | |
dc.description.abstract | Genetic variation is the fuel of evolution, with standing genetic variation especially important for short-term evolution and local adaptation. To date, studies of spatiotemporal patterns of genetic variation in natural populations have been challenging, as comprehensive sampling is logistically difficult, and sequencing of entire populations costly. Here, we address these issues using a collaborative approach, sequencing 48 pooled population samples from 32 locations, and perform the first continent-wide genomic analysis of genetic variation in European Drosophila melanogaster. Our analyses uncover longitudinal population structure, provide evidence for continent-wide selective sweeps, identify candidate genes for local climate adaptation, and document clines in chromosomal inversion and transposable element frequencies. We also characterize variation among populations in the composition of the fly microbiome, and identify five new DNA viruses in our samples. | |
dc.format.extent | 18 | |
dc.format.extent | 5546752 | |
dc.language.iso | eng | |
dc.relation.ispartof | Molecular Biology and Evolution | en |
dc.subject | Adaptation | en |
dc.subject | Clines | en |
dc.subject | Population genomics | en |
dc.subject | Selection | en |
dc.subject | SNPs | en |
dc.subject | Structural variants | en |
dc.subject | Demography | en |
dc.subject | QH301 Biology | en |
dc.subject | Ecology, Evolution, Behavior and Systematics | en |
dc.subject | Molecular Biology | en |
dc.subject | Genetics | en |
dc.subject | DAS | en |
dc.subject | SDG 13 - Climate Action | en |
dc.subject.lcc | QH301 | en |
dc.title | Genomic analysis of European Drosophila melanogaster populations reveals longitudinal structure, continent-wide selection, and previously unknown DNA viruses | en |
dc.type | Journal article | en |
dc.contributor.sponsor | The Wellcome Trust | en |
dc.contributor.institution | University of St Andrews. Centre for Biological Diversity | en |
dc.contributor.institution | University of St Andrews. School of Biology | en |
dc.contributor.institution | University of St Andrews. Institute of Behavioural and Neural Sciences | en |
dc.identifier.doi | 10.1093/molbev/msaa120 | |
dc.description.status | Peer reviewed | en |
dc.identifier.url | https://academic.oup.com/mbe/article/37/9/2661/5837682#supplementary-data | en |
dc.identifier.grantnumber | 105621/Z/14/Z | en |
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