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dc.contributor.authorGilbert, Sophie H.
dc.contributor.authorFuentes, José A.
dc.contributor.authorCordes, David B.
dc.contributor.authorSlawin, Alexandra M. Z.
dc.contributor.authorClarke, Matthew L.
dc.date.accessioned2020-06-23T10:30:01Z
dc.date.available2020-06-23T10:30:01Z
dc.date.issued2020-05-25
dc.identifier.citationGilbert , S H , Fuentes , J A , Cordes , D B , Slawin , A M Z & Clarke , M L 2020 , ' Phospholane-phosphite ligands for Rh catalyzed enantioselective conjugate addition : unusually reactive catalysts for challenging couplings ' , European Journal of Organic Chemistry , vol. 2020 , no. 20 , pp. 3071-3076 . https://doi.org/10.1002/ejoc.202000336en
dc.identifier.issn1434-193X
dc.identifier.otherPURE: 267900542
dc.identifier.otherPURE UUID: a4196d8d-dd1a-4765-885f-895488dc5ad2
dc.identifier.otherRIS: urn:3D49A3D577D06068C1A562768F812626
dc.identifier.otherORCID: /0000-0002-9527-6418/work/74117831
dc.identifier.otherORCID: /0000-0002-2444-1244/work/74117839
dc.identifier.otherORCID: /0000-0002-5366-9168/work/74117879
dc.identifier.otherScopus: 85085133905
dc.identifier.otherWOS: 000531284900001
dc.identifier.urihttp://hdl.handle.net/10023/20126
dc.descriptionWe would like to thank the University of St Andrews, and the EPSRC Centre for Doctoral Training in Critical Resource Catalysis (CRITICAT) for financial support [Ph.D. studentship to SG; Grant code: EP/L016419/1], and the EPSRC for funding of JAF (EP/M003868/1).en
dc.description.abstractThe use of Rh catalysts derived from a phospholane-phosphite ligand were found to be more productive than the classic rhodium/BINAP system in enantioselective conjugate additions. These catalysts enable the use of lower amounts of aryl boronic acid in an asymmetric arylation reaction that required an impractical excess of nucleophile. This catalyst was also found to enable the coupling of a poorly reactive Michael acceptor, N-CBz-2-3-dehydro-4-piperidone, or the coupling of poorly reactive 2-furyl boronic acids at ambient or near temperatures.
dc.language.isoeng
dc.relation.ispartofEuropean Journal of Organic Chemistryen
dc.rightsCopyright © 2020 The Authors. Published by Wiley‐VCH Verlag GmbH & Co. KGaA. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.en
dc.subjectAsymmetric arylationen
dc.subjectMichael additionen
dc.subjectAryl boronic acidsen
dc.subjectPhospholane ligandsen
dc.subjectAsymmetric catalysisen
dc.subjectQD Chemistryen
dc.subjectDASen
dc.subject.lccQDen
dc.titlePhospholane-phosphite ligands for Rh catalyzed enantioselective conjugate addition : unusually reactive catalysts for challenging couplingsen
dc.typeJournal articleen
dc.description.versionPublisher PDFen
dc.contributor.institutionUniversity of St Andrews.School of Chemistryen
dc.contributor.institutionUniversity of St Andrews.EaSTCHEMen
dc.identifier.doihttps://doi.org/10.1002/ejoc.202000336
dc.description.statusPeer revieweden


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