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Phospholane-phosphite ligands for Rh catalyzed enantioselective conjugate addition : unusually reactive catalysts for challenging couplings
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dc.contributor.author | Gilbert, Sophie H. | |
dc.contributor.author | Fuentes, José A. | |
dc.contributor.author | Cordes, David B. | |
dc.contributor.author | Slawin, Alexandra M. Z. | |
dc.contributor.author | Clarke, Matthew L. | |
dc.date.accessioned | 2020-06-23T10:30:01Z | |
dc.date.available | 2020-06-23T10:30:01Z | |
dc.date.issued | 2020-05-25 | |
dc.identifier | 267900542 | |
dc.identifier | a4196d8d-dd1a-4765-885f-895488dc5ad2 | |
dc.identifier | 85085133905 | |
dc.identifier | 000531284900001 | |
dc.identifier.citation | Gilbert , S H , Fuentes , J A , Cordes , D B , Slawin , A M Z & Clarke , M L 2020 , ' Phospholane-phosphite ligands for Rh catalyzed enantioselective conjugate addition : unusually reactive catalysts for challenging couplings ' , European Journal of Organic Chemistry , vol. 2020 , no. 20 , pp. 3071-3076 . https://doi.org/10.1002/ejoc.202000336 | en |
dc.identifier.issn | 1434-193X | |
dc.identifier.other | RIS: urn:3D49A3D577D06068C1A562768F812626 | |
dc.identifier.other | ORCID: /0000-0002-9527-6418/work/74117831 | |
dc.identifier.other | ORCID: /0000-0002-2444-1244/work/74117839 | |
dc.identifier.other | ORCID: /0000-0002-5366-9168/work/74117879 | |
dc.identifier.uri | https://hdl.handle.net/10023/20126 | |
dc.description | We would like to thank the University of St Andrews, and the EPSRC Centre for Doctoral Training in Critical Resource Catalysis (CRITICAT) for financial support [Ph.D. studentship to SG; Grant code: EP/L016419/1], and the EPSRC for funding of JAF (EP/M003868/1). | en |
dc.description.abstract | The use of Rh catalysts derived from a phospholane-phosphite ligand were found to be more productive than the classic rhodium/BINAP system in enantioselective conjugate additions. These catalysts enable the use of lower amounts of aryl boronic acid in an asymmetric arylation reaction that required an impractical excess of nucleophile. This catalyst was also found to enable the coupling of a poorly reactive Michael acceptor, N-CBz-2-3-dehydro-4-piperidone, or the coupling of poorly reactive 2-furyl boronic acids at ambient or near temperatures. | |
dc.format.extent | 1031347 | |
dc.language.iso | eng | |
dc.relation.ispartof | European Journal of Organic Chemistry | en |
dc.subject | Asymmetric arylation | en |
dc.subject | Michael addition | en |
dc.subject | Aryl boronic acids | en |
dc.subject | Phospholane ligands | en |
dc.subject | Asymmetric catalysis | en |
dc.subject | QD Chemistry | en |
dc.subject | DAS | en |
dc.subject.lcc | QD | en |
dc.title | Phospholane-phosphite ligands for Rh catalyzed enantioselective conjugate addition : unusually reactive catalysts for challenging couplings | en |
dc.type | Journal article | en |
dc.contributor.sponsor | EPSRC | en |
dc.contributor.sponsor | EPSRC | en |
dc.contributor.institution | University of St Andrews. School of Chemistry | en |
dc.contributor.institution | University of St Andrews. EaSTCHEM | en |
dc.identifier.doi | https://doi.org/10.1002/ejoc.202000336 | |
dc.description.status | Peer reviewed | en |
dc.identifier.grantnumber | EP/M003868/1 | en |
dc.identifier.grantnumber | EP/L016419/1 | en |
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