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COVID-19 pandemic - A focused review for clinicians
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dc.contributor.author | Cevik, Muge | |
dc.contributor.author | Bamford, Connor | |
dc.contributor.author | Ho, Antonia | |
dc.date.accessioned | 2020-05-13T15:30:03Z | |
dc.date.available | 2020-05-13T15:30:03Z | |
dc.date.issued | 2020-04-25 | |
dc.identifier | 267728569 | |
dc.identifier | eb0c2e54-6ac4-4076-8a86-09135f1ed757 | |
dc.identifier | 32344166 | |
dc.identifier | 85084617606 | |
dc.identifier | 000544273300010 | |
dc.identifier.citation | Cevik , M , Bamford , C & Ho , A 2020 , ' COVID-19 pandemic - A focused review for clinicians ' , Clinical Microbiology and Infection , vol. In press . https://doi.org/10.1016/j.cmi.2020.04.023 | en |
dc.identifier.issn | 1198-743X | |
dc.identifier.other | PubMedCentral: PMC7182753 | |
dc.identifier.uri | https://hdl.handle.net/10023/19934 | |
dc.description.abstract | BACKGROUND: The COVID-19 pandemic caused by SARS-CoV-2 remains a significant issue for global health, economics and society. A wealth of data has been generated since its emergence in December 2019 and it is vital for clinicians to keep up with this data from across the world at a time of uncertainty and constantly evolving guidelines and clinical practice. OBJECTIVES: Here we provide an update for clinicians on the recent developments about virology, diagnostics, clinical presentation, viral shedding, and treatment options for COVID-19 based on current literature. SOURCES: We considered published peer-reviewed papers and non-peer-reviewed pre-print manuscripts on COVID19 and related aspects with an emphasis on clinical management aspects. CONTENT: We describe the virological characteristics of SARS-CoV-2 and clinical course of COVID-19 with an emphasis on diagnostic challenges, duration of viral shedding, severity markers and current treatment options. IMPLICATIONS: The key challenge in managing COVID-19 remains the patient density. However, accurate diagnoses as well as early identification and management of high-risk severe cases are important for many clinicians. For improved management of cases, there is a need to understand test probability of serology, qRT-PCR and radiological testing, and the efficacy of available treatment options that could be used in severe cases with a high risk of mortality. | |
dc.format.extent | 346122 | |
dc.language.iso | eng | |
dc.relation.ispartof | Clinical Microbiology and Infection | en |
dc.subject | Coronavirus | en |
dc.subject | COVID-19 | en |
dc.subject | Novel coronavirus | en |
dc.subject | SARS-CoV-2 | en |
dc.subject | RA0421 Public health. Hygiene. Preventive Medicine | en |
dc.subject | SDG 3 - Good Health and Well-being | en |
dc.subject.lcc | RA0421 | en |
dc.title | COVID-19 pandemic - A focused review for clinicians | en |
dc.type | Journal item | en |
dc.contributor.institution | University of St Andrews. School of Medicine | en |
dc.contributor.institution | University of St Andrews. Infection and Global Health Division | en |
dc.identifier.doi | 10.1016/j.cmi.2020.04.023 | |
dc.description.status | Peer reviewed | en |
dc.identifier.url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182753/ | en |
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