Structure and cleavage of monosodium urate monohydrate crystals

Molloy, Rachael; Sun, Weihao; Chen, Jialu; Zhou, Wuzong

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Date

17/01/2019

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Abstract

The structural study of monosodium urate monohydrate, as the principal component in gout stones, reveals that a simple and biocompatible way to breakdown the crystals into polymerised molecules at pH of 7.4 (the acidity of normal human blood) is to peel off them along the [001] direction by sonication.

Citation

Molloy , R , Sun , W , Chen , J & Zhou , W 2019 , ' Structure and cleavage of monosodium urate monohydrate crystals ' , Chemical Communications , vol. In press . https://doi.org/10.1039/C8CC10050K

Publication

Chemical Communications

Status

Peer reviewed

DOI

https://doi.org/10.1039/C8CC10050K

ISSN

1359-7345

Type

Journal article

Rights

Copyright © 2019 The Author(s). This work has been made available online in accordance with the publisher’s policies. This is the author created, accepted version manuscript following peer review and may differ slightly from the final published version. The final published version of this work is available at https://doi.org/10.1039/C8CC10050K

Collections

University of St Andrews Research

URI

http://hdl.handle.net/10023/19298