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dc.contributor.authorConti, Aldo Alberto
dc.contributor.authorMcLean, Lauren
dc.contributor.authorTolomeo, Serenella
dc.contributor.authorSteele, Douglas
dc.contributor.authorBaldacchino, Alexander Mario
dc.identifier.citationConti , A A , McLean , L , Tolomeo , S , Steele , D & Baldacchino , A M 2019 , ' Chronic tobacco smoking and neuropsychological impairments : a systematic review and meta-analysis ' , Neuroscience and Biobehavioral Reviews , vol. 96 , pp. 143-154 .
dc.identifier.otherPURE: 256689370
dc.identifier.otherPURE UUID: 2d5096ad-064d-450d-a33a-15ee080c7996
dc.identifier.otherScopus: 85057438972
dc.identifier.otherWOS: 000457657300011
dc.description.abstractThe link between neuropsychological impairments and chronic tobacco smoking is not clear and in the current literature there is a lack of robust analyses investigating this association. A systematic review of the literature was conducted in order to identify relevant longitudinal and cross-sectional studies conducted from 1946 to 2017. A meta-analysis was performed from 24 studies testing the performance of chronic tobacco smokers compared with non-smokers on neuropsychological tests related to eight different neuropsychological domains. The results revealed a cross-sectional association between neuropsychological impairments and chronic tobacco smoking in cognitive impulsivity, non-planning impulsivity, attention, intelligence, short term memory, long term memory, and cognitive flexibility, with the largest effect size being related to cognitive impulsivity (SDM = 0.881, p <0.005), and the smallest effect size being related to intelligence (SDM = 0.164, p < 0.05) according to Cohen’s benchmark criteria. No association was found between chronic smoking and motor impulsivity (SDM = 0.105, p = 0.248). Future research is needed to investigate further this association by focusing on better methodologies and alternative methods for nicotine administration.
dc.relation.ispartofNeuroscience and Biobehavioral Reviewsen
dc.rights© 2018, International Behavioral Neuroscience Society, published by Elsevier Ltd. This work has been made available online in accordance with the publisher's policies. This is the author created accepted version manuscript following peer review and as such may differ slightly from the final published version. The final published version of this work is available at
dc.subjectChronic smokingen
dc.subjectCognitive flexibilityen
dc.subjectRA0421 Public health. Hygiene. Preventive Medicineen
dc.subjectRC0321 Neuroscience. Biological psychiatry. Neuropsychiatryen
dc.titleChronic tobacco smoking and neuropsychological impairments : a systematic review and meta-analysisen
dc.typeJournal itemen
dc.contributor.institutionUniversity of St Andrews.School of Medicineen
dc.contributor.institutionUniversity of St Andrews.Population and Behavioural Science Divisionen
dc.contributor.institutionUniversity of St Andrews.Centre for Minorities Research (CMR)en
dc.description.statusPeer revieweden

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