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dc.contributor.authorCzauderna, Christine F.
dc.contributor.authorSlawin, Alexandra M. Z.
dc.contributor.authorCordes, David B.
dc.contributor.authorvan der Vlugt, Jarl Ivar
dc.contributor.authorKamer, Paul C.J.
dc.date.accessioned2019-11-14T00:36:33Z
dc.date.available2019-11-14T00:36:33Z
dc.date.issued2019-01-03
dc.identifier256600831
dc.identifier340224fa-6d48-451d-839e-01e9c3743eca
dc.identifier85057038238
dc.identifier000454466700007
dc.identifier.citationCzauderna , C F , Slawin , A M Z , Cordes , D B , van der Vlugt , J I & Kamer , P C J 2019 , ' P-stereogenic wide bite angle diphosphine ligands ' , Tetrahedron , vol. 75 , no. 1 , pp. 47-56 . https://doi.org/10.1016/j.tet.2018.10.070en
dc.identifier.issn0040-4020
dc.identifier.otherRIS: urn:1FF60D084F51EF83821A2650B0820D19
dc.identifier.otherORCID: /0000-0002-5366-9168/work/50743953
dc.identifier.otherORCID: /0000-0002-9527-6418/work/56861719
dc.identifier.urihttps://hdl.handle.net/10023/18916
dc.descriptionThis work was supported by an EASTCHEM fellowship. We would like to acknowledge the European Union for additional funding through a Marie Curie Excellence Grant MEXT-2004-014320 and COST action CM0802 PhoSciNet.en
dc.description.abstractTwo modular synthetic approaches for the preparation of novel wide bite angle diphosphine ligands containing stereogenic P-atoms have been developed, leading to compounds (S,S)-2,2′-bis(methylphenylphosphino)diphenyl ether (L1) and (S,S)-2,2′-bis(ferrocenylphenylphosphino)diphenyl ether (L2) in very good diastereomeric ratios. Both protocols involve diphenyl ether as backbone and (2RP,4SC,5RC)-(+)-3,4-dimethyl-2,5-diphenyl-1,3,2-oxazaphospholidine borane (RP)-5 as initial auxiliary to induce chirality at phosphorus. The absolute configuration of intermediates (S,S)-9-(BH3)2 and (R,R)-10-(BH3)2 as well as the ligands (S,S)-L1-BH3 and (S,S)-L2 was determined by X-ray crystallographic analysis.
dc.format.extent738876
dc.language.isoeng
dc.relation.ispartofTetrahedronen
dc.subjectP-stereogenic liganden
dc.subjectWide bite angle liganden
dc.subjectEphedrineen
dc.subjectPhosphinite boraneen
dc.subjectOxazaphospholidineen
dc.subjectQD Chemistryen
dc.subjectDASen
dc.subject.lccQDen
dc.titleP-stereogenic wide bite angle diphosphine ligandsen
dc.typeJournal articleen
dc.contributor.institutionUniversity of St Andrews. EaSTCHEMen
dc.contributor.institutionUniversity of St Andrews. School of Chemistryen
dc.identifier.doi10.1016/j.tet.2018.10.070
dc.description.statusPeer revieweden
dc.date.embargoedUntil2019-11-14


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